| SCIENTIFIC PUBLICATIONS:
Okoh, M.P. and Vihinen, M. (1999) Pleckstrin homology
domains of Tec family protein kinases.Biochem.Biophys.Res.Comm., 265;
151-157.
Hansson, H., Okoh, M.P., Smith, C.I.E., Vihinen, M., and Härd, T.
(2001) Intermolecular interactions between the SH3 domain and the proline-rich
TH region of Bruton's tyrosine kinase FEBS. Lett. 489; 67-70.
Okoh, M.P. and Vihinen, M. (2002) interaction between Btk TH and SH3 domain.
Biopolymers 63; 325-334.
Okoh, M.P., Lappalainen, I., Ollila, J., Stenberg, K., and Vihinen, M.
(2001) Structure-function relationships of Bruton's tyrosine kinase (Btk).
Recent Res. Dev. Prot. Eng. (in press)
Okoh, M.P., Lappalainen, I., Ollila, J., Stenberg, K., and Vihinen, M.
(2001) Bruton's tyrosine Kinase (BTK): A protein implicated in the human
X-linked agammaglobulinemia (XLA). Proceedings of the first Mali symposium
on applied sciences; 160-
Okoh, M.P., Kainulainen, L., Heiskanen, K., Nizam Isa, M., Varming, K., Ruuskainen, O. and Vihinen, M. (2002) Novel insertions of Bruton tyrosine kinase in patients with X-linked agammaglobulinemia. Human mutat. in press
Okoh, M.P., Lappalainen, I., Stenberg, K., Pasanen, T. and Vihinen, M. (2002) Ligand Binding and Stability of Four N-Terminal Domains of Btk. Manuscript
Thesis:
Ph.D: Molecular and biophysical analysis of the
non-catalytic PH, TH, SH3 and SH2 domains of Bruton tyrosine kinase (Btk)
protein. (2002) University of Helsinki, Finland
M.Sc: Molecular cloning and functional characterization
of spectrin SH3 domain. (1996) University of Oulu, Finland.
Abstracts/Posters:
Okoh, M.P. and Vihinen, M. (2002) Base Excision
Sequence Scanning (BESS) An Alternative Method For Immune Deficiency Diagnosis:
A Case Study Of Patients With X-Linked Aggammaglobulinemia. Xth meeting
of the European Society For Immunodeficiency (ESID). Weimar, Germany
Okoh, M.P. and Vihinen, M (2002) Intra-/Inter molecular interaction of
Bruton tyrosine kinase (Btk) involving the TH and The SH3 domain. First
International Conference on Biomedical Spectroscopy: From Molecule to
Men. Cardiff, UK
Okoh, M.P. and Vihinen, M (2000) Intramolecular regulation of TEC family
kinases: Circular dichroism spectroscopy of Btk SH3 domain. Signal transduction
pathways and regulation of gene expression as therapeutic target, Luxembourg.
Okoh, M.P. and Vihinen, M (1999) Analysis of ligand induced conformational
changes in Btk-SH3 domain. FASEB summer conference on protein tyrosine
kinases and phosphorylation, Colorado, USA.
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