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Clostridium Difficile Infection in Patients with Inflammatory Bowel Disease

Show simple item record 2017-04-18T09:41:00Z 2017-04-18T09:41:00Z 2017-04-18
dc.title Clostridium Difficile Infection in Patients with Inflammatory Bowel Disease en
ethesis.discipline Gastroenterology en
ethesis.discipline Infectious Diseases en
ethesis.discipline Gastroenterologia fi
ethesis.discipline Infektiosairaudet fi
ethesis.discipline Gastroenterologi sv
ethesis.discipline Infektionssjukdomar sv
ethesis.faculty Faculty of Medicine en
ethesis.faculty Medicinska fakulteten sv
ethesis.faculty Lääketieteellinen tiedekunta fi
ethesis.faculty.URI Helsingfors universitet sv University of Helsinki en Helsingin yliopisto fi
dct.creator Vitikainen, Krista
dct.issued 2017
dct.language.ISO639-2 eng
dct.abstract Patients with inflammatory bowel disease (IBD) are at increased risk for developing symptomatic Clostridium difficile infection (CDI) with worse clinical outcomes, including mortality, as compared with the general population. IBD-patients are also more susceptible to have recurrences of CDI. At present, predisposing factors for CDI in IBD-patients are poorly established. To characterize IBD-related CDI, a retrospective cohort from HUS register was gathered. Patient characteristics were compared with two control groups: IBD-patients with CDI and CDI-patients. According to our results, there was no statistically significant difference in mortality rate between IBD- and CDI-patients in contrary to previous reports. We detected corticosteroid consumption in IBD patients with CDI to be greater than in patient with IBD alone. It could be considered as a risk factor for CDI. Clarifying risk factors for CDI could lead to better understanding of optimal treatment for CDI in IBD patients. en
dct.subject IBD
dct.subject CDI
dct.subject recurrenct infections en
dct.subject risk factors en
dct.language en
ethesis.language English en
ethesis.language englanti fi
ethesis.language engelska sv
ethesis.supervisor Arkkila, Perttu
ethesis.thesistype pro gradu-avhandlingar sv
ethesis.thesistype pro gradu -tutkielmat fi
ethesis.thesistype master's thesis en
dct.identifier.ethesis E-thesisID:b4e40b2e-9feb-45b5-a280-54c45b14e9ab
ethesis.degreeprogram Lääketieteen koulutusohjelma fi
ethesis.degreeprogram Medical curriculum en
ethesis.degreeprogram Medicinska utbildningsprogrammet sv
ethesis-internal.timestamp.reviewStep 2017-02-23 14:27:15:579
dct.identifier.urn URN:NBN:fi:hulib-201704183902
dc.type.dcmitype Text
dct.subject.mesh Tulehdukselliset suolistosairaudet fi
dct.subject.mesh Klostridi-infektiot fi

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