Browsing by Subject "Diet"
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(2020)Objective. Depression is associated with increased risk of chronic disease, which may be at least partly due to poor health behaviors. Growing body of evidence has associated depression with unhealthy diet. However, the association of depression with diet quality in the long run is not well known. Furthermore, it is unclear if dietary interventions could mitigate the harmful association of depression with diet. This study examined the association of depression with diet both cross-sectionally and longitudinally in a population-based prospective cohort. The effectiveness of an early-onset dietary intervention in modifying these associations was investigated. Methods. The sample (n = 457) was from The Special Turku Coronary Risk Factor Intervention Project (STRIP). The intervention group (n = 209) had undergone a dietary intervention lasting from age of 7 months until age of 20 years. Depression was measured at age 20 using Beck Depression Inventory II (BDI-II). Diet quality was assessed at ages 20 and 26 using a diet score calculated based on food diaries. Missing values were replaced using multiple imputation by chained equations. Linear regression analyses were used to analyze the association of depression at age 20 with diet at ages 20 and 26, as well as the modifying effect of intervention group on these associations. Results. No cross-sectional association was found for depression and diet at age 20. Depression at age 20 was longitudinally associated with worse diet quality at age 26. The associations did not differ between intervention and control groups at either of the time points. Conclusions. Contrary to previous research, this study did not find cross-sectional association for depression with diet. However, this study offers novel information on longitudinal associations, suggesting that depression may have effects on diet quality that can manifest after several years. Dietary intervention was not found effective in modifying these associations. Since long-term effects on diet may be an important factor explaining the association of depression with chronic diseases, ways to mitigate the adverse consequences of depression for diet should be explored further.
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(2020)Lipoproteins are biochemical carriers of the insoluble lipids. They are complexes combining lipids and proteins for the transport of lipids. Amongst the type of lipoproteins are low-density lipoproteins (LDL) which are prevalent in various diseases such as obesity, diabetes, atherosclerosis, and other cardiovascular diseases (CVD). Omega-3 fatty acids are polyunsaturated fatty acids (PUFA) that are essential components of lipid metabolism and play a significant role in the human diet. Omega-3 PUFAs such as eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA) are derived from fish and are necessary for proper cardiovascular functioning. Because the human body is unable to produce enough quantities of some omega-3, diet is an important source for its availability. When a diet is rich in saturated fats, the above-mentioned diseases transpire. This study investigated how consumption of two fish diets, Lean fish and Fatty fish, influence the lipid species of human LDL particles. The lipid species analysed in this study are phospholipids such as phosphatidylcholine (PC), sphingomyelin (SM), and lysophosphatidylcholine (LPC), and cholesteryl esters (CE), and triacylglycerols (TAG). A total of 42 volunteers with a history of impaired fasting glucose had randomly been divided into two groups: fatty fish (4 fish meals/week) and lean fish (4 fish meals/week) for 12 weeks. Blood samples had been collected from the volunteers before and after consumption of the fish meals and LDL particles had been isolated from the blood samples by ultracentrifugation. In this study, the lipids were extracted by Folch method, and the extracted lipids were analysed using Triple quadrupole mass spectrometry. The lipid class profile did not change due to the two fish type diets. However, the consumption of fatty fish diet increased the levels of lipid species of PC, LPC, and CE containing EPA and DHA acyl chains, while decreasing levels of several TAG species. Lean fish induced minor changes in the lipid composition of LDL particles. Based on these results, fatty fish diet alters the plasma LDL lipidome profile with changes induced to both the surface and the core composition of the LDL particles in a positive way regarding cardiovascular health.
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(2023)We assessed the association between hair cortisol concentration (HCC), a biomarker for long-term stress, and pre-schoolers’ diet on the macronutrient level in this cross-sectional study. The data was collected in 2015-16 from a population of 655 Finnish children of ages 3-6 years. Hair samples of 2cm from the scalp were collected to represent the HCC from the past two months. Macronutrient intake was examined using food diaries filled out by the parents and Early childhood education and Care (ECEC) on behalf of the pre-schoolers. For the socioeconomic status (SES) the parents reported their highest education level reached and family income. We evaluated the association between the pre-schoolers’ HCC and energy percentage (E%) macronutrient intake with univariate and multiple linear regression models. We evaluated three models which we adjusted for varying confounders; Model 1 had no adjustments, model 2 was adjusted with the ISO BMI and energy intake (KJ) and Model 3 had further adjustments with the highest education level and the relative household monthly income. There was no association found between the pre-schoolers’ HCC and macronutrient intake. Our results are in line with a previous study which also assessed the association between HCC and macronutrient intake in E% but not in g/day. Further studies are needed to gain a deeper understanding of the relationship between HCC and macronutrient intake in young children.
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(2024)Since mercury (Hg) may biomagnify in food webs and bioaccumulate in living things, it is considered a dangerous element globally. The two most toxic forms of mercury are methyl mercury (MgHg) and dimethyl mercury (DMgHg). The dietary Hg consumed by fish is mostly removed through the intestine, but some of the MeHg bioaccumulates and is delivered to various organs, such as the liver, kidney, muscle, or gonad. The perch (Perca fluviatilis), the national fish of Finland serves as both a popular food fish and a monitoring species for assessing the chemical health of lakes. Fish tissue exhibits seasonal variations in mercury levels, which are thought to be produced by growth dilution in the summer, which is related to rapid somatic growth during the growing season, and hunger in the winter, which condenses mercury in the muscle as well as during spawning since gonad development requires significant energy expenditure. There has been a considerable study on Hg concentration in fish but currently lack knowledge regarding potential seasonal variation in patterns of Hg content and bioaccumulation to understand the dynamics of Hg content and bioaccumulation. This study investigates (Q1): Does mercury content change in muscle, liver and gonad tissues of males and females of perch over the four seasons? (Q2): How does mercury bioaccumulation change seasonally in different organs between male and female perch? (Q3): How does the mercury content relationship among different organs (muscle, liver, and gonads) vary seasonally and between sexes? Materials were collected monthly from Lake Pääjärvi from April 2020 to March 2021, and categorized into four seasons: winter (January -March), spring (April-Jun), summer (July-September), and autumn (October-December). Each fish was taken of its length, weight, sex, and other tissues too. Total mercury (Hg) concentrations were determined in three organs (muscle, liver and gonad) in male and female perch separately. Using analysis of variance, the annual length-corrected THg content variation and simple linear regression analysis were used to examine the annual THg bioaccumulation variation and to test the relationships in Hg concentrations among three tissues separately in males and females. Seasonal THg levels in female perch significantly varied in muscle and gonads, not in the liver. Females had consistently higher THg in muscle and liver, while males had higher levels in gonads throughout the season. THg bioaccumulation peaked in spring and winter for both sexes in muscle, but lowest in autumn. Liver THg slope was highest in early summer for females and lowest in autumn. Gonads showed the highest slopes in summer for both sexes. The highest slopes between muscle and liver THg for females were in summer and for males in spring. Similar patterns were seen in both muscle-gonad and liver-gonad THg relationships. Female perch showed significant differences only in summer, while in males, the highest slopes were in autumn and lowest in summer. Long-term monitoring is crucial to understanding THg variation in fish.
Now showing items 1-4 of 4