Skip to main content
Login | Suomeksi | På svenska | In English

The diagnosis of pre-eclampsia using two revised classifications in the Finnish Pre-eclampsia Consortium (FINNPEC) cohort

Show simple item record 2016-06-09T09:52:45Z 2017-08-01T21:00:34Z 2016-06-09
dc.title The diagnosis of pre-eclampsia using two revised classifications in the Finnish Pre-eclampsia Consortium (FINNPEC) cohort en
ethesis.discipline Gynecology en
ethesis.discipline Gynekologia ja obstetriikka fi
ethesis.discipline Gynekologi sv
ethesis.faculty Medicinska fakulteten sv
ethesis.faculty Lääketieteellinen tiedekunta fi
ethesis.faculty Faculty of Medicine en
ethesis.faculty.URI Helsingfors universitet sv University of Helsinki en Helsingin yliopisto fi
dct.creator Kallela, Jenni
dct.creator Jääskeläinen, Tiina
dct.creator Kortelainen, Eija
dct.creator Laivuori, Hannele
dct.issued 2016
dct.language.ISO639-2 eng
dct.abstract Background The Finnish Pre-eclampsia Consortium (FINNPEC) case-control cohort consisting of 1447 pre-eclamptic and 1068 non-pre-eclamptic women was recruited at the five Finnish university hospitals to study genetic background of pre-eclampsia and fetal growth. Pre-eclampsia was defined by hypertension and proteinuria according to the modified The American College of Obstetricians and Gynecologists (ACOG) 2002 classification. The ACOG Task Force Report on Hypertension in Pregnancy (2013) and The international Society for the Study of Hypertension in Pregnancy (ISSHP) (2014) have published new classifications, which change the paradigm that the diagnosis of preeclampsia always requires proteinuria. Here we studied how the new classifications would affect the pre-eclampsia diagnoses in the FINNPEC cohort. Methods We re-evaluated pre-eclampsia diagnosis using the ACOG 2013 and the ISSHP 2014 classifications in those pre-eclamptic women with the amount of proteinuria not exceeding 1+ in dipstick (N=68) and in women with gestational hypertension (N=138). Results Number of women with pre-eclampsia increased 0.5% (1454/1447) according to the ACOG 2013 criteria and decreased 0.9% (1434/1447) according to the ISSHP 2014 criteria. All 68 women with the amount of proteinuria not exceeding 1+ in dipstick diagnosed originally pre-eclamptic met the ACOG 2013 criteria but only 20 women (29.4%) met the ISSHP 2014 criteria. Seven (5.1%) and 35 (25.4%) women with gestational hypertension were diagnosed with pre-eclampsia according to the ACOG 2013 and the ISSHP 2014 criteria, respectively. Conclusions Only minor changes were observed in the total number of pre-eclamptic women in the FINNPEC cohort when comparing the modified ACOC 2002 classification with the ACOG 2013 and ISSHP 2014 classifications. en
dct.subject Pre-eclampsia en
dct.subject hypertension en
dct.subject proteinuria en
dct.subject classification en
dct.subject criteria en
dct.language en
ethesis.language English en
ethesis.language englanti fi
ethesis.language engelska sv
ethesis.supervisor Laivuori, Hannele
ethesis.thesistype pro gradu-avhandlingar sv
ethesis.thesistype pro gradu -tutkielmat fi
ethesis.thesistype master's thesis en
dct.identifier.ethesis E-thesisID:a716f7ea-c5d1-44b3-bc13-4146dc9f484c
ethesis.degreeprogram Lääketieteen koulutusohjelma fi
ethesis.degreeprogram Medical curriculum en
ethesis.degreeprogram Medicinska utbildningsprogrammet sv
ethesis-internal.timestamp.reviewStep 2016-05-11 08:49:16:659
dct.identifier.urn URN:NBN:fi:hulib-201606092276
dc.type.dcmitype Text

Files in this item

Files Size Format View
Jenni Kallela, tutkielma 10.5.2016.docx 154.9Kb Microsoft Word 2007

This item appears in the following Collection(s)

Show simple item record