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Transcriptional analysis of Trichoderma reesei under conditions inducing cellulase and hemicellulase production, and identification of factors influencing protein production

Mari Häkkinen

Utilisation of non-edible, renewable lignocellulosic biomass for the production of second generation biofuels and chemicals is hindered especially by the high price of enzymes needed for biomass degradation. Filamentous fungi are natural producers of enzymes active against plant cell wall polymers. Especially the ascomycota fungus Trichoderma reesei is widely utilised in the industry for...

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Väitöstilaisuus: 29.10.2014

Immunotoxicological effects induced by engineered nanomaterials

Jaana Palomäki

Engineered nanomaterials (ENM) are widely used in the industry as their unique characteristics improve competitiveness and potential for innovations in the different sectors of industry: It has been estimated that the market size of nanotechnological innovations will exceed 2 trillion euros in 2015. However, the toxicological hazard and risk assessment of different nanomaterials is far f...

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Väitöstilaisuus: 31.10.2014

Glycan Binding Proteins in Therapeutic Mesenchymal Stem Cell Research

Tia Hirvonen

Mesenchymal stem/stromal cells (MSCs) are multipotent adult stem cells that hold enormous therapeutic potential. They are currently in a focus of intense clinical and scientific investigation. MSCs are a promising cell type for various applications in the field of tissue engineering due to their multi-lineage differentiation capacity. Furthermore, one of their most interesting characteri...

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Väitöstilaisuus: 31.10.2014

In the Name of Vivir Bien : Indigeneity, State Formation and Politics in Evo Morales' Bolivia

Eija M. Ranta

This is an ethnographic study of the politics of indigeneity in the contemporary Bolivian state transformation process. It is a story of an attempt to transform the state through indigenous ideas in a poor and ethnically heterogeneous country in the Global South. By following the notion of vivir bien, good life, a term that has emerged in Bolivia s political and policy discourses since t...

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Väitöstilaisuus: 31.10.2014

Pathobiology of Heterobasidion-conifer tree interaction: molecular analysis of antimicrobial peptide genes (Sp-AMPs)

Emad Jaber

Little information is available concerning the interaction of Heterobasidion annosum with the roots of herbaceous angiosperm plants. We investigated the infec¬tion biology of H. annosum during challenge with the angi¬osperm model Arabidopsis and monitored the host response after exposure to various hormone elicitors, chemicals (chitin, glucan and chitosan) and fungal species. This necrot...

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Väitöstilaisuus: 31.10.2014

Tracking cereulide producing Bacillus cereus in foods, papermaking and biowaste management

Douwe Hoornstra

Bacillus cereus is a ubiquitous food poisoning bacterium, but only producers of the emetic toxin, cereulide can be life threatening. Therefore a fast and reliable method is needed for identifying strains that produce the toxin. In this thesis the previously developed sperm bioassay was refined into a tool for the detection of microbially produced mitochondria toxic substances. This refin...

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Väitöstilaisuus: 31.10.2014

Sociolinguistic variation in English derivational productivity : Studies and methods in diachronic corpus linguistics

Tanja Säily

This dissertation studies how the productivity of word-formation varies across social groups in the history of the English language. Previous research into variation and change within the morphological productivity of derivational affixes has been hampered by the lack of suitable methods for comparing productivity measures across subcorpora. A further problem has been how to assess the s...

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Väitöstilaisuus: 31.10.2014

Spatial conservation prioritization for Finnish forest conservation management

Joona Lehtomäki

In a world of competing interests and increasing land use pressures, the allocation of limited resources for biodiversity conservation need to be prioritized. Spatial conservation prioritization deals with the cost-efficient and well-balanced identification of priority areas for biodiversity, as well as with the allocation and scheduling of alternative conservation actions. Finland is th...

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Väitöstilaisuus: 31.10.2014

BIOCHEMICAL EFFECTS OF INHERITED MMR GENE MUTATIONS AND DIET ON COLON CANCER RISK

Denis Dermadi Bebek

Colorectal cancer (CRC) is one of the leading causes of death in developed countries. Although, a small fraction of cancers are caused by inherited genetic predisposition most of the CRCs are sporadic. In CRC, cancer risk is associated with lifestyle factors and aging. Even in dominantly inherited CRC predisposition such as in Lynch syndrome (LS), which is linked to germline mu- tations ...

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Väitöstilaisuus: 31.10.2014

Yhdysvallat ja Saksan koalition pienet maat : Suomen, Romanian ja Unkarin sodanjälkeinen asema Yhdysvaltain ulkoministeriön suunnittelupöydällä vuosina 1942-1945

Ohto Rintala

The study examines the U.S. State Department s postwar foreign policy planning concerning Finland, Romania and Hungary in years 1942-1945. When Germany launched an attack against the Soviet Union in June 1941 these countries took part in the coalition of Germany, while the United States and Stalin s Soviet Union were allies in the war against Hitler s Germany. Finland, Romania and Hungar...

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Väitöstilaisuus: 31.10.2014

The Influence of Weather, Season, Climate, and Disasters on Non-Communicable Diseases

Nadja K. Schreier

Background. The environment has a major impact on human beings. Extreme environmental conditions such as hot temperatures can have huge health impacts, as shown during the heat wave in Europe that occurred during the summer 2003. The main causes of death were non-communicable diseases (NCDs) such as respiratory and cardiovascular diseases. Natural and man-made disasters can cause the col...

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Väitöstilaisuus: 31.10.2014

The Evolutionary Feminism of Zhang Kangkang and the Developing Dialogue between Darwinism and Gender Studies

Qingbo Xu

This dissertation studies the work of Zhang Kangkang (a contemporary Chinese woman writer, 1950- ) in the light of evolutionary feminism (also called Darwinian feminism, which studies gender issues from an evolutionary perspective, brings feminist concerns into the fields of evolutionary biology, psychology and sociobiology, and illuminates and rectifies androcentric biases in these fiel...

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Väitöstilaisuus: 5.11.2014

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Suomalainen perinnöllinen gelsoliiniamyloidoosi – taudin ilmenemisen ja kehittymisen erot miesten ja naisten välillä

Saastamoinen, Aleksi / 24.10.2014

Suomalainen perinnöllinen gelsoliiniamyloidoosi – taudin ilmenemisen ja kehittymisen erot miesten ja naisten välillä Saastamoinen, Aleksi Meretojan tauti eli suomalainen perinnöllinen gelsoliiniamyloidoosi on yksi yleisimmistä suomalaiseen tautiperintöön kuuluvista perinnöllisistä sairauksista. Tutkimuksen tarkoituksena on selvittää taudin ilmenemisen ja kehittymisen eroavaisuuksia miest...

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Subjekti, objekti ja miniteoriat luokanopettajaopiskelijoiden kieliopillisessa ajattelussa

Marjokorpi, Jenni / 24.10.2014

Subjekti, objekti ja miniteoriat luokanopettajaopiskelijoiden kieliopillisessa ajattelussa Marjokorpi, Jenni According to the recent draft of the renewed Finnish national core curriculum, the basic concepts of grammar are to be learned already in the primary school when they are taught by a classroom teacher. As the basis of metalinguistic awareness, the grammatical concepts are complex ...

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"Hyvä, mutta vaikea." Maahanmuuttajien kokemuksia kieliharjoittelústa

Korhonen, Suvi / 24.10.2014

"Hyvä, mutta vaikea." Maahanmuuttajien kokemuksia kieliharjoittelústa Korhonen, Suvi Tutkielmassa tarkastellaan työvoimapoliittisessa kotoutumiskoulutuksessa opiskelevien maahanmuuttajien kokemuksia kieliharjoittelusta. Kieliharjoittelu on neljä viikkoa kestävä työelämäjakso, jonka tavoitteena on aktivoida suullista kielitaitoa ja tutustua suomalaiseen työkulttuuriin. Tutkielma...

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«На чем свет стоит»: сущность знаковых мест в конструкции светского пространства в журнале Tatler

Simpanen, Julia / 24.10.2014

«На чем свет стоит»: сущность знаковых мест в конструкции светского пространства в журнале Tatler Simpanen, Julia Tutkielmassa tarkastellaan ulkomailla sijaitsevien merkkipaikkojen olemusta venäläisen seurapiiritilan konstruktiossa. Työssä havaittiin, ettei venäläinen seurapiiritila rajoitu vain Venäjän valtiollisten rajojen sisälle, vaan se on mobiililta luonteeltaan kytköksissä myös Ve...

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