Suomeksi |  På svenska |  In English

Selaa tai hae opinnäytteitä

Vienan Karjalan asutushistoria nimistön valossa

Denis Kuzmin

Väitöskirjatutkimuksen kohteena on Vienan Karjalan asutuksen muodostuminen ennen kaikkea paikannimistön valossa. Väitöstutkimuksen pääosa koostuu kuudesta artikkelista, joiden keskeisenä teemana on nykyisen Karjalan tasavallan pohjoisosien etninen historia. Tutkimus keskittyy historiallisissa lähteissä mainittuihin etnisiin ryhmiin kuten saamelaisiin, karjalaisiin, hämäläisiin, savolaisi...

Lue väitöskirja »

Väitöstilaisuus: 27.8.2014

Pseudopeptides and Peptidomimetics Modulating the Proteolytic Activity of Kallikrein-related Peptidase 3

Kristian Meinander

The highly prostate specific serine protease kallikrein-related peptidase 3 (KLK3, also known as prostate specific antigen, PSA) is widely used as a biomarker for prostate cancer and it has also been postulated that it may play a part in tumour growth. Especially interestesting is the antiangiogenic effect exerted by proteolytically active KLK3 in cell line models. In order to stimulate ...

Lue väitöskirja »

Väitöstilaisuus: 28.8.2014

Micronuclei in Human peripheral Lymphocytes - Mechanistic Origin and Use as a Biomarker of Genotoxic Effects in Occupational Exosure

Ghita Falck

The formation of micronuclei (MN) in peripheral blood lymphocytes represents one of the earliest cytogenetic effects of exposure to genotoxic carcinogens. An increased frequency of MN and of other cytogenetic alterations, such as chromosomal aberrations and sister chromatid exchanges, in a well-controlled study of occupationally exposed people, is usually considered a strong indication o...

Lue väitöskirja »

Väitöstilaisuus: 29.8.2014

Second language lexis and the idiom principle

Svetlana Vetchinnikova

This work sets out to examine how second language (L2) users of English acquire, use and process lexical items. For this purpose three types of data were collected from five non-native students of the University of Helsinki. First, each student s drafts of Master s thesis chapters written over a period of time were compiled into a language usage corpus. Second, academic publications a st...

Lue väitöskirja »

Väitöstilaisuus: 29.8.2014

Russian Greatpowerness: Foreign policy, the Two Chechen Wars and International Organisations

Hanna Smith

This dissertation addresses the difficulties encountered in international relations between Russia and the West, specifically Europe, in spite of their cultural and geographical proximity and the expectation that Russia and Europe would share values and interests following the collapse of the Soviet Union. The problem is addressed through focussing on a particular aspect of Russia s nati...

Lue väitöskirja »

Väitöstilaisuus: 29.8.2014

A taxonomic revision of the Taeniidae Ludwig, 1886 based on molecular phylogenies

Antti Lavikainen

The most pathogenic zoonotic cestodes of humans belong to the family Taeniidae. Members of this family (taeniids) are parasites of mammals requiring predatory definitive hosts and herbivorous or omnivorous intermediate hosts. Due to the major medical, veterinary and economic importance, taeniids have been a topic of intensive taxonomic, ecological and epidemiological studies resulting in...

Lue väitöskirja »

Väitöstilaisuus: 29.8.2014

Porous Silicon-Based Multicomposites for Controlled Drug Delivery

Dongfei Liu

The co-loading of different therapeutic molecules into a single carrier offers several advantages over individual administration. The aim of this dissertation was to develop a robust platform that would enable precise control over the loading and release of different drug cargos to facilitate combination therapy.

Lue väitöskirja »

Väitöstilaisuus: 29.8.2014

Ischaemia-Reperfusion-Induced Kidney Injury : Experimental studies on the effects of caloric restriction, AMPK activator AICAR and α2-adrenoceptor agonists in the rat

Juha Lempiäinen

Ischaemia-reperfusion (I/R) injury of the kidneys is a common cause of acute kidney injury (AKI). The incidence of AKI among hospitalized patients is between 2-10%, and the mortality rates are high. Currently there is no medication for AKI. The aim of the present study was to increase our knowledge of the pathophysiological mechanisms underlying ischaemic AKI and to identify tentative dr...

Lue väitöskirja »

Väitöstilaisuus: 29.8.2014

Development of organotypic liver cell cultures in three-dimensional biomaterial hydrogels

Melina Malinen

New organotypic liver cell cultures are needed to predict the metabolism, excretion, and safety of chemical compounds. Liver cell models are particularly important since the liver largely regulates the ultimate fate of compounds in the body. Approximately 70% of the drugs administered to the body are metabolized or excreted by the liver.

Lue väitöskirja »

Väitöstilaisuus: 1.9.2014

Crib-biting in Horses: A Physiological and Genetic Study of Candidate Causative Factors

Karin Hemmann

Crib-biting in horses is an oral stereotypy. A crib-biting horse grasps a fixed object with its incisor teeth, contracts the lower neck muscles to retract the larynx caudally and draws air into the cranial oesophagus while emitting a characteristic grunt. The prevalence of crib-biting varies among equine populations from 1.8% to 15%. Free-ranging horses are not known to crib-bite. The ai...

Lue väitöskirja »

Väitöstilaisuus: 5.9.2014

Staphylococcus aureus bacteraemia - Disease progression and prognosis

Erik Forsblom

Introduction. Staphylococcus aureus bacteraemia (bloodstream infection) (SAB) is increasingly common in both community and hospital settings. The presence of deep infection focus is pathognomonic for SAB and deep infection foci should be meticulously searched for and eradicated whenever possible. However, despite effective antistaphylococcal antibiotics, radiological investigations and s...

Lue väitöskirja »

Väitöstilaisuus: 6.9.2014

Cell encapsulation in hydrogels for long-term protein delivery and tissue engineering applications

Leena-Stiina Kontturi

Cell therapy is defined as cell transplantation into the patient to treat a certain disease state. Therapies utilizing cells can be divided into two main categories, (1) tissue regeneration or engineering and (2) drug delivery. In tissue engineering, the transplanted cells are used to regenerate the functions of a diseased tissue. In drug delivery, the transplanted cells are used as biol...

Lue väitöskirja »

Väitöstilaisuus: 6.9.2014

Lisää »

Yyterin eolisen aineksen provenanssi

Niemelä, Jussi / 27.08.2014

Yyterin eolisen aineksen provenanssi Niemelä, Jussi Yyterin dyynikentät ovat muodostuneet Porista luoteeseen, selkämereen pistävän Yyterinniemen länsirannalle. Alueen kallioperä on Jotunista Satakunnan hiekkakiveä, joka alueen pintaosissa vaihtelee arkoosisesta areniitista subarkoosiin. Maaperämuodostumat alueella ovat pääosin moreeni- ja harjukerrostumia, jotka luoteesta virrannut manne...

Lue opinnäyte »

Pellon vuokrahintaan vaikuttavat tekijät Suomessa-vuokraviljelijän näkökulma

Ala-Kleemola, Katri / 26.08.2014

Pellon vuokrahintaan vaikuttavat tekijät Suomessa-vuokraviljelijän näkökulma Ala-Kleemola, Katri Maanvuokraus on yleistynyt viime vuosikymmeninä nopeasti Suomessa, mutta siitä huolimatta vuokrahintoja ei toistaiseksi ole tilastoitu säännöllisesti. Tässä tutkimuksessa tutkitaan niitä tekijöitä, jotka vaikuttavat pellon vuokrahintaan Suomessa. Tutkimuksen teoreettisen osuuden tavoitteena o...

Lue opinnäyte »

The effect of 5,6-dimethylbenzimidazole on vitamin B12 synthesis and protein production in Propionibacterium freudenreichii ssp. freudenreichii

Ishchenko, Tatiana / 26.08.2014

The effect of 5,6-dimethylbenzimidazole on vitamin B12 synthesis and protein production in Propionibacterium freudenreichii ssp. freudenreichii Ishchenko, Tatiana Propionibacterium freudenreichii is commonly known as a Swiss-type cheese ripening culture, and is also frequently applied in the industrial production of vitamin B12 (cobalamin). One way to increase vitamin B12 productivity is...

Lue opinnäyte »

Lämpökäsittelyn vaikutus vihannesten väriin ja rakenteeseen

Mustanoja, Ella / 21.08.2014

Lämpökäsittelyn vaikutus vihannesten väriin ja rakenteeseen Mustanoja, Ella Tutkielman kirjallisuusosassa perehdyttiin värikkäisiin vihanneksiin ja yleisimpiin vihanneksissa esiintyviin väriaineisiin, joita ovat karotenoidit, antosyaanit, betalaiinit ja klorofylli. Lisäksi selvitettiin miten lämpökäsittelyt vaikuttavat näihin väriaineisiin ja vihannesten rakenteeseen. Kokeellisen työn...

Lue opinnäyte »

Lisää »