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Methods for assessing degrading effects of UV radiation on materials

Anu Heikkilä

UV radiation is one of the key factors ageing materials and thus limiting their service life time. Damages induced by UV radiation may be observed as changes in the properties of the material. Various types of weathering experiments are used to study the chemical and physical mechanisms behind the degradation process. Material samples are exposed to UV radiation and other environmental s...

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Public examination: 3.10.2014

Bayesian regularized regression methods for quantitative genetics with focus on longitudinal data

Zitong Li

Quantitative trait loci (QTL) /association mapping aims to identify the genomic loci associated with the complex traits. From a statistical perspective, multiple linear regression is often used to model, estimate and test the effects of molecular markers on a trait. With genotype data derived from contemporary genomics techniques, however, the number of markers typically exceed the numbe...

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Public examination: 3.10.2014

Method development for the analysis of steroids, vitamin D and oxysterols

Linda Ahonen

Steroids, vitamin D and oxysterols are all part of a group of compounds called lipids, which are generally important in the function of the human body and in many cases the monitoring of these analytes can be of high value. Therefore, the development of a sensitive and universal method, suitable for the simultaneous analysis of these compounds, is of a great importance. In this study, th...

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Public examination: 3.10.2014

Complications in Ankle Fracture Surgery

Mikko Ovaska

Ankle fractures are among the most frequently encountered surgically treated fractures. The operative treatment of this fracture may be associated with several complications. The most frequently encountered complications are related wound healing, and deep infection may have devastating consequences. As the population continues to age, the number of elderly patients with comorbidities su...

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Public examination: 3.10.2014

Completed and attempted suicides in relation to weather and daylight in Finland : Register based study from 1969 to 2010

Laura Hiltunen

Suicides and attempted suicides in relation to weather and daylight in Finland, from 1969 to 2010 Suicide statistics show higher figures during spring and summer compared to autumn and winter. No explanation to this phenomenon has been found, but seasonal changes in weather have been suspected to be involved. The objective of this study was to find out whether correlation between suicide...

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Public examination: 10.10.2014

Bovine B cells: Antibody repertoire diversification in fetal cattle

Jenni Liljavirta

The majority of research studies on immunological mechanisms have been conducted in human or rodent models and the results are generalized in respect of other vertebrates. However, the generation of B cells varies considerably between species. B cells are produced in the bone marrow of rodents and humans throughout life. The initial antibody diversity is produced by the random assembly o...

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Public examination: 10.10.2014

The regulation of U12-dependent splicing and its significance to mRNA stability

Elina Niemelä

The removal of noncoding sequences, or introns, from eukaryotic messenger RNAs is an essential step in the expression of genetic information. Two types of introns are removed by dedicated spliceosomes. The majority of introns are spliced by the U2-dependent spliceosome, whereas a small fraction of introns, less than 0.5%, are removed by a dedicated U12-dependent spliceosome. Although the...

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Public examination: 10.10.2014

Database-wide studies on the validity of the Geocentric Axial Dipole hypothesis in the Precambrian

Toni Veikkolainen

A branch of science concentrated on studying the evolution of the Earth's magnetic field has emerged in the last half century. This is called paleomagnetism, and its applications include calculations of field directions and intensity in the past, plate tectonic reconstructions, variations in the conditions in the Earth s deep interior and the climatic history. With the increasing quantit...

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Public examination: 10.10.2014

Microbial Community Profiling of Biodegradable Municipal Solid Waste Treatments : Aerobic Composting and Anaerobic Digestion

Dan Yu

An enormous quantity of solid waste is generated annually all over the world. Solid waste can be divided into three main categories: municipal waste, industrial waste and agricultural waste. The focus of the research presented in this thesis was on the biodegradable fraction of municipal solid waste (MSW), and particularly on the biowaste and sewage sludge generated in the Nordic countri...

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Public examination: 10.10.2014

Dairy cow behaviour in relation to health, welfare and milking

Jutta Kauppi

Animal welfare includes both physiological and mental health and is affected by several external and internal factors. In dairy cows, human care and the ability of the cows to cope with daily challenges are the most significant factors. The research presented in this dissertation focused on cow behaviour and aspects impacting on behavioural changes during mastitis and milking. To deepen ...

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Public examination: 10.10.2014

VEGF-A and VEGF-C in Experimental Obliterative Bronchiolitis

Rainer Krebs

The aim of this study was to investigate the role of VEGF ligands A and C and their receptors (VEGFR-1, VEGFR-2, VEGFR-3) in the development of experimental OB. To this effect, tracheal allografts were transplanted heterotopically into MHC-mismatched mice and rats. In the heterotopic tracheal allograft model, an early inflammatory phase with its peak at 10 days after transplantation is f...

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Public examination: 10.10.2014

Characterization of synchrotron radiation based functional lung imaging

Satu Strengell

Functional lung CT using synchrotron radiation was applied for studying regional ventilation distribution in vivo in animal lungs. This quantitative method employs the K-edge subtraction (KES) technique, which takes advantage of the sharp rise of the absorption coefficient at the binding energy of K-shell electron of a contrast agent. In KES technique two images are taken simultaneously ...

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Public examination: 10.10.2014

Jumalan lähetys : Georg Friedrich Vicedomin missio Dei -mallin rakenne ja ekumeeninen konteksti

Timo-Matti Haapiainen

The aim of this study is 1) to analyse the substance and the structure of the missiological model in the writings of the German missionary and missiologist Georg Friedrich Vicedom (1903 1974) and 2) to compare Vicedom s model with its contemporaries in ecumenical discourse. The focus is on two themes in Vicedom s texts: the fundamental theological basis and the ecclesiological dimensions...

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Public examination: 10.10.2014

Tehokkuuden toiveuni : Uuden julkisjohtamisen historia Suomessa 1970-luvulta 1990-luvulle

Ville Yliaska

This study explores the birth and development of marketisation of public sector in Finland since the 1970s. These quasi-market reforms were labeled as New Public Management (NPM) in the 1990s. The main idea of NPM was to cre¬ate competition and result-oriented management into the public sector. The main focus is put on three different reforms: management by results reform, state subsidy ...

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Public examination: 11.10.2014

Topikövergång i textbaserade gruppsamtal

Melina Bister

This study examines how Finnish university students learning Swedish perform text-based group discussion tasks in their target language. The focus is on the participants interaction at the transitions between different contentually defined parts of the discussions, i.e., topic transitions. The material consists of five group discussions with a total length of 128 minutes, based on three ...

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Public examination: 11.10.2014

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Sukupuoli- ja seksuaalivähemmistöihin kuuluvien vanhusten kohtaaminen pitkäaikaisessa laitoshoidossa - hoitajien näkökulma

Valtonen, Saini / 01.10.2014

Sukupuoli- ja seksuaalivähemmistöihin kuuluvien vanhusten kohtaaminen pitkäaikaisessa laitoshoidossa - hoitajien näkökulma Valtonen, Saini Tutkielmassa selvitetään hoitotyöntekijöiden käsityksiä sukupuoli- ja seksuaalivähemmistöihin kuuluvien vanhusten kohtaamisesta pitkäaikaisen laitoshoidon kontekstissa. Tutkimuksen liikkeellepanijana on Seta ry:n kolmivuotinen Yhdenvertainen vanhuus -...

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Kohti johtajuutta, vakautta ja vaikutusvaltaa - Sosiaalidemokraatit ja kokoomus eduskunnan Emu-keskusteluissa toukokuussa 1997 ja huhtikuussa 1998

Mäkelä, Jouni / 01.10.2014

Kohti johtajuutta, vakautta ja vaikutusvaltaa - Sosiaalidemokraatit ja kokoomus eduskunnan Emu-keskusteluissa toukokuussa 1997 ja huhtikuussa 1998 Mäkelä, Jouni Tutkielmassa tarkastellaan 1990-luvun lopun suurimpien suomalaisten hallituspuolueiden, Sdp:n ja kokoomuksen, Eu-roopan talous- ja rahaliittoon (Emu) liittymisen puolesta esittämiä perusteluja sekä liittymispäätöksestä käytyä ed...

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Finlandssomalisk identitet i ett nytt medielandskap: En undersökning om kulturell identitet och medieanvändning bland andra generationens somaliska ungdomar i Finland

Itäinen, Sandra / 01.10.2014

Finlandssomalisk identitet i ett nytt medielandskap: En undersökning om kulturell identitet och medieanvändning bland andra generationens somaliska ungdomar i Finland Itäinen, Sandra Avhandlingen undersöker hurudana kulturella identitetskonstruktioner och konstruktioner av kulturell tillhörighet som uppstår då andra generationens somaliska ungdomar talar om sin medieanvändning. Kulturer ...

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Pekka ja muut pelottomat - Yleinen etu ja lähdesuoja argumentaation haasteena Sonera-kirjan ympärille muodostuneessa julkisuudessa vuosina 2002-2010

Koskipahta, Elina / 01.10.2014

Pekka ja muut pelottomat - Yleinen etu ja lähdesuoja argumentaation haasteena Sonera-kirjan ympärille muodostuneessa julkisuudessa vuosina 2002-2010 Koskipahta, Elina Lähdesuojaa käsittelevää tutkimusta on tehty Suomessa erittäin vähän. Pro gradu -tutkielman taustana on Helsingin yliopiston viestinnän tutkimuskeskus CRC:ssä vuosina 2010-2011 tehty lähdesuojatutkimus, jonka tutkimusavust...

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