The haemodynamic and pharmacologic interaction of medetomidine and peripheral antagonist MK-467 and their dose-dependency in dogs
The alpha-2 agonist, medetomidine (MED), and its pure active enantiomer dexmedetomidine (DMED), are in clinical use for small animal practice as potent sedatives, analgesic agents, muscle relaxants, and as an adjunct agents for balanced anaesthesia. However, their cardiovascular effects limit their use. The use of constant rate infusion (CRI) for administration of MED was studied in orde...
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Public examination: 28.10.2016