Signalling and expression of the Ang-Tie pathway in tumor vasculature
Angiogenesis, the growth of new blood vessels, is essential during embryonic development, but it is also involved in numerous human diseases, including cancer. Vascular endothelial growth factors (VEGFs) and their receptors (VEGFRs), as well as angiopoietin growth factors (Ang1, Ang2) together with their Tie1 and Tie2 tyrosine kinase receptors are essential regulators of angiogenesis and...
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Public examination: 15.12.2016