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Predictive biomarkers in diffuse gliomas and non-small cell lung cancer

Katja Merkkiniemi

The presence of certain cancer-related genetic and epigenetic alterations in the tumor affect patients´ response to specific cancer therapies. The accurate screening of these predictive biomarkers in molecular diagnostics is important since it enables the tailoring of an optimal treatment based on molecular characteristics of the tumor. Depending on the type of gene alteration, a wide va...

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Public examination: 6.3.2015

Estimation of leaf area index and the fraction of absorbed photosynthetically active radiation in a boreal forest

Titta Majasalmi

The aim of this dissertation is to assess the accuracy of different ground reference methods used to validate satellite based leaf area index (LAI) and the fraction of absorbed photosynthetically active radiation (fPAR) products. LAI and fPAR are strongly linked, although they principally and practically measure different properties: LAI quantifies the areal interphase between soil and a...

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Public examination: 6.3.2015

Association of job strain with sleep and psychophysiological recovery in shift working health care professionals

Kati Karhula

Health care personnel often have irregular working hours and stressful work characteristics, which may challenge employees possibilities to sleep and recover sufficiently. The aim of this study was to examine the association of stressful work characteristics, measured as job strain, with sleep and psychophysiological recovery in shift working health care professionals.

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Public examination: 6.3.2015

Challenges in real-time precision farming: a case study of modelling biomass accumulation

Mikko Hakojärvi

Precision farming is a set of advanced technologies and cultivation practices that aim to enhance crop growing conditions in a site-specific manner. Current machinery offers many technical tools for such actions, but information about when and where it is necessary to use the developed machinery effectively is lacking. The use of crop models has been proposed to combine the effects of gr...

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Public examination: 6.3.2015

Cluster population simulations as a tool to probe particle formation mechanisms

Tinja Olenius

Formation of aerosol particles from condensable vapors is a ubiquitous phenomenon in the atmosphere. Aerosols can affect regional and global climate, as well as visibility and human health. The work of this thesis contributes to the numerous efforts made to build understanding of atmospheric particle formation mechanisms. The focus is on the first molecular-level steps, where clustering ...

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Public examination: 6.3.2015

Tietoa, valtaa ja toimintaa. Suomalaisen valokuvataiteen kansainvälistyminen: Käsitteiden kautta järjestyvä valokuvataiteen kenttä 1990–2000 -luvuilla

Anna-Kaisa Rastenberger

Anna-Kaisa Rastenbergerin tutkimus käsittelee suomalaista valokuvataidetta ja sen kansainvälistymistä viime vuosikymmeninä. Tutkimus koostuu viidestä tapaustutkimuksesta, jotka valaisevat suomalaisen valokuvataiteen lähihistorian kansainvälistymishankkeita, niiden motiiveja, tavoitteita ja vaikutuksia kotimaisen valokuvataiteen kenttään. Tutkimus tarkastelee valokuvataiteen yhteiskunnall...

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Public examination: 6.3.2015

Diamond-like carbon binding peptides – evolutionary selection, characterization, and engineering

Bartosz Gabryelczyk

The possibility of controlling interactions at interfaces and surfaces of solid materials is highly interesting for a wide range of materials-related nanotechnological applications, for example, colloidal systems, adhesives, biosensors, biomimetic composite and biomedical materials. In Nature, many proteins and peptides possess the ability to recognize, specifically bind, and modify the ...

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Public examination: 6.3.2015

Ultrasonically Manufactured Space Tether

Henri Seppänen

Tethers are key elements in the electric solar wind sail (E-sail). In this thesis I claim that E-sail tether manufacturing on km scale is possible. The E-sail is a space propulsion method for interplanetary missions. It uses long, thin and conductive, tethers to create thrust from the solar wind. Based on simulations a full scale E-sail using one hundred 20 km long tethers could crea...

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Public examination: 10.3.2015

From turbulence to cloud formation - modelling the aerosol-cloud interactions

Juha Tonttila

Clouds, aerosols and the interactions between them are some of the most important uncertainties in climate modelling. The scales of spatial variability related to clouds are generally too small to be resolved using a typical climate model grid resolution. This work comprises studies about the small-scale variability of the vertical wind component, which significantly contributes to the p...

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Public examination: 10.3.2015

Staying well in an unstable world of work - Prospective cohort study of the determinants of employee well-being

Krista Pahkin

The overarching aim of the thesis was to identify work-related and personal factors which support employee well-being during working career and organizational restructuring. The empirical part of this thesis was based on a prospective cohort study of employees in the Finnish forest industry. Data included responses to questionnaires (N up to 4279) and records from organizational and nati...

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Public examination: 11.3.2015

Stochastic Dynamic Optimization Models in the Banking Sector

Rasmus Ahvenniemi

The thesis consists of an introduction and 3 essays presenting stochastic dynamic optimization models concerning decision making in the banking sector. The first two essays consider individual banks in an environment where financial crises may occur. The third essay considers the whole banking sector as one entity which is a part of the economy, and thereby the process of money creation ...

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Public examination: 13.3.2015

Duck habitat use and reproduction in boreal wetlands: importance of habitat quality and population density

Sari Holopainen

The boreal biome harbours a large share of the world s wetlands, and is the main breeding area for several duck species. Breeding habitats strongly influence duck reproduction. In this study, the habitat use of ducks and their breeding success was estimated in a boreal landscape in southern Finland. A review of duck habitat use in boreal wetlands was additionally made.

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Public examination: 13.3.2015

Jälkivalvonta ympäristönsuojelulaissa - Tutkimus ympäristönsuojelulain jälkivalvontasäännösten soveltamisalojen rajautumisesta

Elina Nyholm

The research question relates to the content of the ex post supervision provisions of the Finnish Environmental Protection Act (EPA) under the currently valid legislation. The study particularly focuses upon single control orders (EPA Section 180), indirect administrative compulsion (EPA Sections 175 through 176) and direct administrative compulsion (EPA Section 181). The objective is to...

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Public examination: 13.3.2015

Studies of diamond-like carbon and diamond-like carbon polymer hybrid coatings deposited with filtered pulsed arc discharge method for biomedical applications

Anttti Soininen

Hydrogen free diamond-like carbon (DLC) coatings have been the subject of investigation all around the world for the last 30 years. One of the major problems in producing of thick high-quality DLC coatings has been the inadequate adhesion of the deposited film to the substrate. This obstacle is finally overcome by depositing an intermediate adhesion layer produced with high energy (>2 ke...

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Public examination: 13.3.2015

Cellulose-based materials

Sara R. Labafzadeh

Worldwide research is focused on the use of renewable and biodegradable raw materials due to the limited existing quantities of fossil supplies and the environmental degradation caused by global warming. Cellulose, derived from natural resources such as wood, annual plants and microbes, represents the most abundant renewable polymeric material on earth. Due to its low cost and functional...

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Public examination: 13.3.2015

Transitivity in Eastern Mansi - An Information Structural Approach

Susanna Virtanen

The dissertation consists of four articles published in peer-reviewed linguistic journals and an introduction. The aim of the study is to provide a description of the formal means of expressing semantic transitivity in the Eastern dialects of the Mansi language (EM), as well as of the variation between the different means. The study is connected to Uralic studies and functional-linguisti...

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Public examination: 14.3.2015

Poetry in Sufi Practice - Patrons, Poets and Performers in South Asian Sufism from Thirteenth Century to the Present

Mikko Viitamäki

This study discusses poetic communication in the context of maḥfil-i samāʿ (an assembly of listening to sung poetry) among South Asian Sufis. Drawing from both textual and ethnographic materials, the study explores the relationship between Sufi practice, poetic expression, and musical performance. It presents a context-sensitive reading of a multilingual (Persian, Hindi, Urdu) poetic cor...

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Public examination: 16.3.2015

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Reitinetsintä ja etsintäavaruudet tietokonepeleissä

Maaranen, Timo / 05.03.2015

Reitinetsintä ja etsintäavaruudet tietokonepeleissä Maaranen, Timo Opinnäytetyö esittelee moderneissa peleissä usein käytettyjä reitinetsintämenetelmiä sekä etsintäavaruuksia, joissa menetelmät toimivat. Se perehdyttää reitinetsinnän periaatteisiin peruasioista lähtien ja sopii siten esimerkiksi johdannoksi aiheeseen. Näkökulmana on käytännönläheinen ja siinä pyritään ottamaan huomioon p...

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ForcePhone: new prototype with pressure and thermal feedback

Coe, Patrick / 05.03.2015

ForcePhone: new prototype with pressure and thermal feedback Coe, Patrick The project worked on goes by the name of “ForcePhone II.” It follows in the footsteps of the previous “ForcePhone” project developed by Nokia Research and the Helsinki Institute of Information Technology. [HSH12] The original ForcePhone took pressure feedback from a caller who would squeeze a phone, in this case a...

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Newton-based Optimization Methods for Noise-Contrastive Estimation

Qaiser, Beenish / 05.03.2015

Newton-based Optimization Methods for Noise-Contrastive Estimation Qaiser, Beenish The main focus of this thesis is on the use of Newton-based optimization methods for the optimiza- tion of an objective function that is used in the estimation of unnormalized statistical models. For these models, the probability density function (pdf) is known only up to a multiplicative normal- izing fac...

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Exploring Software Development as an Experiment System: An Interview-Based Qualitative Survey

Lindgren, Eveliina / 05.03.2015

Exploring Software Development as an Experiment System: An Interview-Based Qualitative Survey Lindgren, Eveliina An experiment-driven approach to software product and service development is getting increasing attention as a way to channel limited resources to the efficient creation of customer value. In this approach, software functionalities are developed incrementally and validated in ...

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