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Personality and work stress: the role of Five-Factor Model traits and cynicism in perceptions of work characteristics

Maria Törnroos

The role of individual differences in perceptions of stress has long been recognized. Despite this, the models that are used to measure stress at the workplace the job strain model and the effort-reward imbalance model were developed to assess strenuous work characteristics and their health effects, regardless of the individual. Because work characteristics are usually measured using sel...

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Disputationen: 24.4.2015

Computational genomics of lactobacilli

Matti Kankainen

Lactobacilli are generally harmless gram-positive lactic acid bacteria and well known for their broad spectrum of beneficial effects on human health and usage in food production. However, relatively little is known at the molecular level about the relationships between lactobacilli and humans and about their food processing abilities. The aim of this thesis was to establish bioinformatic...

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Disputationen: 24.4.2015

Structure-property relationships and self-assembly of chlorophyll derivatives in development of light-harvesting structures and materials

Taru Nikkonen

In photosynthetic systems, chlorophylls have a vital role in converting the energy of light into chemical energy. The absorption by antenna pigments and subsequent excitation energy transfer to the reaction centre, where charge separation processes take place, result in an electrochemical potential which is utilized in carbohydrate production. The structural properties of the chlorophyll...

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Disputationen: 24.4.2015

Induced short estrous cycles in cyclic dairy heifers and cows

Mari H. Rantala

Fertility in dairy cows has decreased worldwide, also in Finland. The most common reason for treatments of dairy cattle is various fertility disorders (18 % of all animals in 2013). In practice, decreased fertility warrants use of hormonal estrus synchronization protocols to control follicular waves and luteal regression to achieve acceptable pregnancy rates, without unwanted side effect...

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Disputationen: 24.4.2015

Abuse and fatal poisonings involving prescription opioids - Revelations from postmortem toxicology

Margareeta Häkkinen

Opioids are the most important drugs causing fatal poisonings. Determining whether an opioid death was poisoning may, however, be difficult even if involving appropriate toxicological laboratory investigation. Apart from heroin, little statistically significant data-analysis is available for interpretation of blood concentrations of opioids from various types of post-mortem cases. Tolera...

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Disputationen: 24.4.2015

Factors Affecting Infection and Detection of the Soilborne Potato Mop-Top Virus

Johanna Santala

The spraing symptoms on potato tubers caused by Potato mop-top virus (PMTV) are considered as one of the most important quality problems in potato production in the Nordic countries. PMTV has a tripartite single stranded positive sense RNA genome. RNA-RdRp encodes the viral replicase. PMTV-CP codes for a coat protein (CP) and a read through part of CP associated with the vector transmiss...

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Disputationen: 24.4.2015

Modern analytical approaches to pharmaceutical powder characterisation and processing

Ira Soppela

The manufacturing of the most common pharmaceutical dosage forms, tablets, requires good mass flowability and uniform particle size distribution. Granulation is often needed to improve these properties prior to tablet compression. Thus, rapid methods for analysing the key powder and granule properties, such as particle size, flowability and moisture content are needed. Until recently, th...

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Disputationen: 24.4.2015

Improving attendance to cervical cancer screening: Effects of HPV-testing on self-taken samples in the Finnish cervical cancer screening programme

Anni Virtanen

High coverage amongst those at risk and a high attendance rate are essential in achieving a good impact in a cervical cancer screening programme. In Finland, attendance in the programme is approximately 70% with a slight decreasing trend. There is wide variation in the current invitation practice between municipalities. The introduction of human papillomavirus (HPV) testing in cervical c...

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Disputationen: 24.4.2015

Developing genetically engineered oncolytic viruses for cancer gene therapy

Suvi Parviainen

It has been estimated that up to half of people living in industrial societies will get cancer. Almost all cancer deaths are caused by metastatic disease and only few metastatic solid tumors can be cured with available therapies. Therefore, novel therapeutic modalities are needed. Genetically engineered oncolytic viruses such as adenoviruses and vaccinia viruses are a promising therapeut...

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Disputationen: 24.4.2015

Integration Platform for Biomedical Image Analysis

Ville Rantanen

Images provide invaluable information to Biomedicine. Especially, microscopy as an information source has been providing knowledge for research and clinical diagnostics. We have moved away from simply looking at the images to quantifiable computerized image analysis. Over the last decades, image analysis developers have prepared algorithms and software to address various scientific enqui...

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Disputationen: 24.4.2015

Development of liquid chromatography mass spectrometric methods for quantification of metabolites from cellular level to clinical biomarkers

Niina Tohmola

Metabolites are low molecular weight compounds participating in different functions of cellular systems. Metabolites can be used as diagnostic biomarkers for numerous diseases. Liquid chromatography tandem mass spectrometry (LC-MS/MS) is a powerful tool in quantification of metabolites from various sample matrices. Good sensitivity and specificity are the main benefits of the technique. ...

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Disputationen: 24.4.2015

Reintegration as Recognition: Ex-combatant and veteran politics in Namibia

Lalli Metsola

This is a study of Namibian ex-combatant and veteran policies after the country s transition to independence in 1990. Instead of assessing the successfulness of reintegration against its stated objectives or the perspective of post-conflict policy discourses, it examines the politics of reintegration as a process of multiform negotiation over recognition and entitlements for the ex-comba...

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Disputationen: 25.4.2015

Reflexive and Passive Categories in Languages of the Volga Region - An Areal Typological Study

Merja Salo

All of the Volga region languages investigated in this study (Mordvin, Mari, and Chuvash) have a rich derivational morphology. In general linguistics terms, they all have a passive classified as a reflexive passive. The relationship between the derivative and the root verb is described using the valence roles of case grammar. The role of the first, or primary, actant is crucial in defini...

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Disputationen: 25.4.2015

Intrauterine contraception - Use in Nulligravid Women and Safety Aspects

Janina Kaislasuo

The proportion of nulligravid and nulliparous women is increasing as women delay childbirth in developed countries. Simultaneously, contraceptive failure, unintended pregnancies and abortions, especially in women below the common childbearing age, are a global problem. By promoting intrauterine devices (IUDs) and subdermal implants, referred to as long-acting reversible contraceptives (L...

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Disputationen: 29.4.2015

Interaction between visual perception and mental representations of imagery and memory in the early visual areas

Elyana Saad

The relationship between mental representations based on external visual percepts (i.e., information held in short-term memory or via mental imagery) and the encoding of visual input remains unsettled. What stimulates this debate is the share of overlapping neural resources between visual short-term memory (VSTM), mental imagery and visual perception in the realm of the early visual cort...

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Disputationen: 5.5.2015

Drivers of ecological and geomorphological patterns in the complex beach system

Tua Nylén

General patterns and processes of the unique land uplift beaches are still insufficiently understood. Advanced modelling methods and large homogeneous datasets provide novel opportunities to analyse spatio-temporal environmental processes. This doctoral thesis aims at expanding on the knowledge of the beach and adjacent coastal dunes as an ecogeomorphic system. More specifically, the the...

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Disputationen: 6.5.2015

Epidemiology of comorbidities in early rheumatoid arthritis: with emphasis on cardiovascular disease

Anne Kerola

Rheumatoid arthritis (RA) is associated with a substantially increased risk for cardiovascular (CV) morbidity and mortality. Along with their CV burden, RA patients are at increased risk for other comorbidities such as hypothyroidism and depressive symptoms. The aim of this work was to evaluate the prevalence of CV comorbidities and hypothyroidism among RA patients in comparison to those...

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Disputationen: 6.5.2015

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Pamela Cooper-Whiten sielunhoidon jaettu viisaus ja sen intuitiivisuus

Salonen, Eveliina / 24.04.2015

Pamela Cooper-Whiten sielunhoidon jaettu viisaus ja sen intuitiivisuus Salonen, Eveliina Tutkimus käsittelee Pamela Cooper-Whiten jaetun viisauden käsitettä ja sen intuitiivisuutta. Tutkimuksessa tarkastellaan sitä, mitä Pamela Cooper-White tarkoittaa sielunhoidossa ilmenevällä jaetulla viisaudella ja kuinka lähinnä psykologian parissa tehdyn intuitiotutkimuksen havaintoja voidaan peilat...

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”Yleensä on vähän niitä, jotka uskaltavat kulkea virtaa vastaan”. Suomalaisen papiston rooli alkoholipoliittisessa keskustelussa keväällä 1932

Aaltonen, Valtteri / 24.04.2015

”Yleensä on vähän niitä, jotka uskaltavat kulkea virtaa vastaan”. Suomalaisen papiston rooli alkoholipoliittisessa keskustelussa keväällä 1932 Aaltonen, Valtteri Vuoden 1932 alkaessa kansanäänestyksen tulos oli selvä. Kieltolailla ei ollut kansan tukea, joten siitä oli luovuttava. Suomen valtion talous oli vuoden 1931 aikana kehittynyt huolestuttavaan suuntaan. Työttömyys oli kasvussa ja...

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Harrastuksia erikoisrippikoulujen kustannuksella? -Kvantitatiivinen tutkimus harrasterippikouluun osallistuneiden nuorten rippikoulukokemuksista vuonna 2013

Meriläinen, Helena / 24.04.2015

Harrastuksia erikoisrippikoulujen kustannuksella? -Kvantitatiivinen tutkimus harrasterippikouluun osallistuneiden nuorten rippikoulukokemuksista vuonna 2013 Meriläinen, Helena Tutkimuksessa tarkastellaan erikois- ja harrasterippikouluja. Rippikoulu on suomessa suosittu ilmiö nuorten keskuudessa ja se tavoittaakin vuosittain yli 80 prosenttia 15-vuotiaista nuorista. Miten on erikois- ja ...

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Angolan evankelisluterilaisen kirkon ensimmäiset viisi vuotta 1991–1996

Salmi, Tuomas / 24.04.2015

Angolan evankelisluterilaisen kirkon ensimmäiset viisi vuotta 1991–1996 Salmi, Tuomas Tässä pro gradu – tutkielmassa käsitellään Angolan evankelisluterilaisen kirkon tapahtumia sen itsenäisyyden ensimmäisenä viitenä vuotena. Tuo kirkko itsenäistyi vuonna 1991 äitikirkostaan Namibian luterilaisesta kirkosta. Vuonna 1994 kirkkoon liittyivät Pohjois-Angolan tunnustukselliset luterilaiset se...

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