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Environmental Impact of Using Phlebiopsis gigantea in Stump Treatment Against Heterobasidion annosum sensu lato and Screening Root Endophytes to Identify Other Novel Control Agents

Eeva-Liisa Terhonen

Scots pine (Pinus sylvestris) and Norway spruce (Picea abies) cover large areas in boreal regions with significant economic importance to Finnish forest industry. Approximately 15% of the spruce trees felled in Finland are rotten and thus commercially less valuable. The majority of this conifer wood decay is due to the root and butt rot pathogen Heterobasidion annosum sensu lato. Extensi...

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Disputationen: 4.9.2015

Developmentally Regulated Induction and Expression Mechanisms of Long-Term Potentiation at Hippocampal CA3–CA1 Synapses

Natalia V. Luchkina

Activity-dependent synaptic plasticity, and long-term potentiation in particular, represents the predominant model of memory and learning at the cellular level. In addition, synaptic plasticity plays a critical role in the activity-dependent refinement and fine-tuning of neuronal circuits during development by maintaining and stabilising certain synaptic connections and eliminating other...

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Disputationen: 4.9.2015

Antibiotic resistance in human impacted environments

Antti Karkman

Increasing microbial resistance against antibiotics is threatening their efficiency in the future and we might be heading back to pre-antibiotic era. Infectious diseases still treatable with antibiotics might soon become life threatening. There is a strong correlation between antibiotic use and antibiotic resistance occurrence. Hotspots for antibiotic resistance are mainly man made such ...

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Disputationen: 4.9.2015

Function spaces and bounded compositions on metric measure spaces

Tomas Soto

The homogeneous Besov spaces B(s,p,q) and the homogeneous Triebel-Lizorkin spaces F(s,p,q) are two scales of function spaces on the Euclidean space that include the standard and fractional-order Sobolev spaces, and arise naturally in the contexts of e.g. partial differential equations and interpolation theory. In the first article presented in this thesis (joint work with H. Koch, P. Kos...

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Disputationen: 4.9.2015

Political effectiveness of agricultural policies - An empirical analysis

Kyösti Arovuori

This dissertation analyses the effectiveness of the Common Agricultural Policy of the European Union. The motivation of this study arises from the fact that there is a lack of empirical research on the effects of policy instruments on the stated policy objectives. In addition, most of the analysis in the literature has focused on the policy objective to secure farmers incomes and, thus, ...

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Disputationen: 4.9.2015

Biomedical Data Integration in Cancer Genomics

Riku Louhimo

Cancer is one of the leading causes of death in industrialized nations and its incidence is steadily increasing due to population aging. Cancer constitutes a group of diseases characterized by unwanted cellular growth which results from random genomic alterations and environmental exposure. Diverse genomic and epigenomic alterations separately and jointly regulate gene expression and sti...

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Disputationen: 4.9.2015

RAD51C IS A TUMOR SUPPRESSOR IN MAMMARY AND SEBACEOUS GLANDS

Manuela Tumiati

Breast cancer is the second most common cancer in the world and the most common cancer among women. Germ-line mutations in the DNA repair gene RAD51C (RAD51 paralog C) predispose women to breast and ovarian cancers, yet the mechanisms by which a lack of RAD51C causes tumorigenesis are poorly understood. RAD51C deficiency is thought to promote cancer by preventing correct repair of DNA do...

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Disputationen: 8.9.2015

Focusing on arts education from the perspectives of learning, wellbeing, environment and multiprofessional collaboration - Evaluation research of an arts education project in early childhood education centres and schools

Saila Nevanen

This research focuses on one arts education project which was carried out in Helsinki in early childhood education centres and schools. This study is an evaluation research which concentrates on art education s connections to learning, wellbeing and communality; it views kindergarten and school as arts learning environments and at arts education as a multiprofessional col-laboration betw...

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Disputationen: 11.9.2015

Self-promotion as semiotic behavior - The mediation of personhood in light of Finnish online dating advertisements

Tomi Visakko

The study examines the mediation and evaluation of personhood in light of Finnish online dating advertisements. The main focus is on the performance and interpretation of what has been called self-promotion, or the idealization of the self in relation to others. The study operates with concepts originating from discourse studies and anthropology under the overarching framework of pragmat...

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Disputationen: 11.9.2015

To be or not to be a Queen - Caste-specific gene expression patterns in ants

Claire Morandin

Understanding how the interaction of genotypes and environment may result in distinct phenotypes from similar sets of genes is a central theme in evolutionary biology. Social insects have been important study organisms for this question, with sociality evolving in parallel in unrelated taxa. The defining feature of advanced sociality, the separate reproductive queen and non-reproductive ...

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Disputationen: 11.9.2015

Who is serving whom? - An agency-for perspective on enterprise promotion in rural Finland

Miira Niska

Entrepreneurship is expected to serve a multitude of societal interests. It is assumed to enhance competitiveness, create jobs and services, and contribute to social and ecological development. As such, enterprise promotion has become an integral part of Finnish policymaking. In the rural context, enterprise promotion is an essential part of regional, agricultural and rural policies. Con...

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Disputationen: 11.9.2015

Phylogeny, symbiotic interactions and chemical variation in the genus Bryoria section Implexae (Parmeliaceae, Lecanoromycetes)

Hanna Lindgren

Lichens are symbiotic associations of heterotrophic fungi and photoautotrophic green algae or cyanobacteria. Bryoria is a lichenized euascomycete genus of approximately 50 currently accepted species. Although Bryoria is a conspicuous, easily recognized and frequently collected genus, species boundaries in this group are poorly known. This is especially the case with species in section Im...

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Disputationen: 11.9.2015

Ocular and systemic pharmacokinetic models for drug discovery and development

Eva Maria del Amo Paez

Drug discovery and development is a long process: it takes usually 12 to 15 years before a drug candidate reaches the market. The pharmacokinetics of the drug is an important aspect of drug discovery and development, because the drug must reach its target site and exert the therapeutic response. The pharmacokinetic parameters of new compounds should be investigated early in drug discover...

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Disputationen: 11.9.2015

Anxiety, depression, and anger in the borderland of chronic pain

Peter Knaster

Chronic pain is a long-lasting burdensome condition. Comorbid psychological symptoms are common in chronic pain patients and they tend to worsen the treatment outcome. The aim of this cross-sectional study was to assess the prevalence of psychiatric comorbidity in chronic pain patients and to assess the associations between chronic pain, anxiety, anger, and depression.

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Disputationen: 11.9.2015

Generation, characterization and sizing of sub-3 nm nanoparticles and molecular clusters

Juha Kangasluoma

Atmospheric aerosols exhibit the largest uncertainties in the radiative forcings of the Earth s climate. A large fraction of the uncertainties originates from the aerosol-cloud in-teractions, a process which is not understood completely. Understanding the processes related to aerosol formation and growth will help to narrow down these uncertainties and understand the anthropogenic fracti...

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Disputationen: 16.9.2015

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Skönlitteratur i finsk översättning i det finska litterära polysystemet under perioden 1900-1999 : Hurdana översättningsnormer kan rekonstrueras ur översättningskritiken i tidskriften Valvoja och dess efterträdare under 1900-talet?

Punsar, Ville / 20.08.2015

Skönlitteratur i finsk översättning i det finska litterära polysystemet under perioden 1900-1999 : Hurdana översättningsnormer kan rekonstrueras ur översättningskritiken i tidskriften Valvoja och dess efterträdare under 1900-talet? Punsar, Ville Tutkielmani käsittelee suomennetun kaunokirjallisuuden vastaanottoa 1900-luvulla kulttuurilehti Valvojassa sekä sen nk. seuraajissa, joita ovat ...

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Ei-sanalliset ainekset afasiakeskustelussa

Partanen, Elina / 26.08.2015

Ei-sanalliset ainekset afasiakeskustelussa; Nonverbal elements in aphasia converation Partanen, Elina Tavoitteet: Afaattisten henkilöiden käyttämiä kehollisia vuorovaikutuskäytänteitä on toistaiseksi tutkittu suhteellisen vähän. Tämän tutkimuksen tarkoituksena oli kuvata vaikeasti afaattisen henkilön ja hänen puolisonsa välistä vapaata keskusteluvuorovaikutusta. Pyrin selvittämään, milla...

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Ruoan uskonnolliset merkitykset yläkoulun uskonnon oppikirjoissa

Heikkilä Astrid / 26.08.2015

Ruoan uskonnolliset merkitykset yläkoulun uskonnon oppikirjoissa; Food Religious Meanings in Middle School Religion Textbooks Heikkilä Astrid Tämän tutkimuksen lähtökohtana on ruoan ja uskontojen monipuolinen suhde, joka esiintyy kaikissa uskonnoissa. Tutkimuksen kohteena ovat koulun uskonnonopetus ja siinä erityisesti oppikirjat. Tutkimuksessa ruokaa ja ruoan ympärille liitettäviä uskon...

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På tal om kön : Talutrymme, uppbackningar, skratt och könsuppfattningar i ungdomssamtal

Koskinen, Katja / 24.08.2015

På tal om kön : Talutrymme, uppbackningar, skratt och könsuppfattningar i ungdomssamtal Koskinen, Katja Tutkielman tavoitteena on tarkastella sekä sukupuolen vaikutusta keskusteluun että keskustelua sukupuolesta. Tutkimusaineistona käytetään viiden nuoren leiri-illan aikana nauhoittamaa 90 minuutin pituista äänitallennetta. Tutkittavat vuorovaikutukselliset ilmiöt ovat puhetilan jakautum...

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