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Immune Responses to Pathogen Infection in Arabidopsis

Mantas Survila

To survive, plants must recognize the presence of danger and establish effective defenses against invading pathogens. Most plants are resistant to the majority of plant pathogens. This passive protection is provided primarily by the cell wall and waxy cuticular layer that limit the progress of most attackers. If these barriers are overcome, the second line of defense is triggered upon de...

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Public examination: 28.4.2017

The Making of a Global Elite - Global Economy and the Davos Man in the Financial Times 2001–2011

Markus Ojala

Recent decades have seen an increase in the number of international forums and media that focus on current issues of the world economy and politics. They bring decision-makers from the spheres of politics, business and administration into a common conversation, and connect powerful individuals around the globe. This study defines these institutions as spaces for transnational elite commu...

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Public examination: 28.4.2017

Laryngeal cancer recurrence - Prognostic factors and management

Aaro Haapaniemi

Laryngeal cancer is one of the most common head and neck cancers. The treatment of laryngeal squamous cell carcinoma (LSCC) has evolved towards non-surgical treatment, namely radiotherapy and chemoradiotherapy. However, the treatment outcome of LSCC has not improved. LSCC recurs in up to 30% of patients. The current knowledge on prognostic factors for recurrence is too limited to aid in ...

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Public examination: 28.4.2017

Learning from Medication Errors in Healthcare – How to Make Medication Error Reporting Systems Work?

Anna-Riia Holmström

Medication errors are one of the most common incidents leading to adverse events in healthcare worldwide. Tackling these major problems requires the implementation of a systems approach to healthcare, stating that risks should be managed proactively by improving the healthcare system. One of the recommended key strategies for learning from medication errors and risk prone processes is th...

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Public examination: 28.4.2017

Presence of hepatitis E virus (HEV) and markers for HEV infection in production swine, human patients with unexplained hepatitis, and veterinarians in Finland

Tuija Kantala

Hepatitis E virus (HEV) infections are common in both humans and animals. HEV genotypes 1 and 2 (HEV-1 and HEV-2) only infect humans and are endemic to Asia, Africa, and Central America, where they cause large, usually waterborne hepatitis epidemics. HEV-3 and HEV-4 are zoonotic and in addition to humans, they also infect animals. Especially HEV-3 is common in swine globally. The porcine...

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Public examination: 28.4.2017

Diagnosis of acute appendicitis: Diagnostic scoring and significance of preoperative delay

Henna Sammalkorpi

Background and aims: Diagnostic scoring is a method for stratifying patients according to the probability of appendicitis, and therefore works as an excellent basis for a diagnostic algorithm. This study aimed at developing a new diagnostic score, the Adult Appendicitis Score (AAS), and validating its routine use as an integral part of a new diagnostic algorithm. Diagnostic accuracy of t...

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Public examination: 28.4.2017

INFLUENCE OF BIRTH WEIGHT ON THE RISK AND CLINICAL PRESENTATION OF SCHIZOPHRENIA

Asko Wegelius

Pre- and perinatal environmental factors have been associated with increased schizophrenia risk, particularly in combination with genetic liability. Both low and high birth weight have been associated with an increased risk of autism spectrum disorders and schizophrenia. The interaction of specific schizophrenia susceptibility genes and specified pre- and perinatal environmental factors ...

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Public examination: 28.4.2017

Microcredit, Production System and Technical Efficiency of Smallholder Rice Production in Northern Ghana

Benjamin Tetteh Anang

The purpose of the study was to evaluate technical efficiency in smallholder rice production and how it relates to the production system and participation in agricultural microcredit in Northern Ghana. Smallholder farmers play an important role in agricultural production in Ghana and account for about 80 percent of domestic food production. However, smallholders continue to face challeng...

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Public examination: 28.4.2017

Refashioning the Respectable Elite Woman in Louis XIV’s Paris - Madame de Sévigné and Ninon de Lenclos

Riikka-Maria Pöllä

This PhD thesis is an analysis of the appearances, material culture and sexuality of the respectable woman, l honneste femme, in Paris under the regime of Louis XIV. Through the examples of Madame de Sévigné and Ninon de Lenclos, the study describes how Parisian elite women were able to fashion the ideal of l honneste femme and how reality and ideals were combined in Parisian society. Th...

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Public examination: 28.4.2017

Studies on Proteins Influencing Cancer Progression and Regulating Endocytic Lipid Trafficking

Boris Vassilev

Endocytosis is a form of active cellular transport by which cells internalize molecules from the extracellular environment. This thesis studies proteins involved in endocytosis that influence the progression of cancers in humans. Two of the three articles summarized here employ cell biological experiments to elucidate the role of the proteins N-muc downstream-regulated gene 1 (NDRG1) and...

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Public examination: 28.4.2017

Fighting Bugs by Numbers: Bioinformatics Tools for Antimicrobial Drug Discovery

Andreas Helfenstein

onding to the aggravating shortage of potent antibiotics, pharmaceutical research is constantly looking for new ideas to combat and contain perilous micro-organisms. As a result of persistent selective pressure, evolution has bestowed a powerful arsenal of antimicrobial survival strategies upon plants, bacteria and fungi.

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Public examination: 28.4.2017

Happy Ship? - Etnografinen tutkimus suomalaisista ja filippiiniläisistä merimiehistä suomalaisilla rahtilaivoilla

Anne Ala-Pöllänen

Tarkastelen tutkimuksessani Suomen lipun alla purjehtivilla rahtilaivoilla työskentelevien miehistöjen laivaelämää keskittyen miehistön yhteistyöhön ja arjen rakentumiseen työyhteisössä. Kohteena olevat laivat olivat sekamiehitettyjä, mikä tarkoitti kolmea kansallisuutta, suomalaisia, virolaisia ja filippiiniläisiä samassa miehistössä. Aineistoni pohjalta selvitän, minkälaisen inhimillis...

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Public examination: 29.4.2017

Paleobiogeographic and Paleoecologic Development of the Old World Savanna Paleobiome during the Neogene

Ferhat Kaya

The study of paleobiogeographic development of Old World Neogene mammalian faunas has a long history. During the last decade further fossil data improvements and advancement in methods along with a focus on the context of paleoclimate change have offered new insights to reconstructing the paleobiogeographic development of the Negoene mammal communities. Recent studies produced with these...

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Public examination: 2.5.2017

Geochemical impacts on the release of silicon within entire watersheds

Virpi Siipola

This thesis focused on the bioreactive pools of silicon (Si) in sediments and phenomena affecting Si release from sediments. There are several potentially mobile pools of Si in sediment, e.g. biogenic Si (BSi), dissolved Si, and adsorbed Si (AdSi). These various Si pools make the investigation of a single pool challenging because of the interference caused by other Si pools. To evaluate ...

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Public examination: 5.5.2017

Metabolic and inflammatory factors in upper extremity soft-tissue disorders

Martti Rechardt

Upper extremity soft tissue disorders (UESTDs) are common painful conditions relating to tendons and their adjacent structures. The etiology of UESTDs, particularly the role of metabolic and inflammatory factors, is unknown. Some studies have found associations between obesity and diabetes with UESTDs. To date, few studies have assessed the role of cytokines in UESTDs and virtually nothi...

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Public examination: 5.5.2017

Socioeconomic status and health among the elderly Chinese people-A longitudinal study

Lei Yang

The association between socioeconomic status and health has been well studied. It has been found that people in higher social classes generally have better health and a lower mortality. However, it is still inconclusive whether the health advantage acquired by people with a higher socioeconomic status weakens in later life. Although empirical evidence in Western societies has revealed di...

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Public examination: 5.5.2017

SAFETY AND EFFICACY OF LOW-MOLECULAR-WEIGHT HEPARIN RELATED TO PREGNANCY AND RISK OF THROMBOEMBOLISM IN THE POSTPARTUM-PERIOD

Päivi Galambosi

Venous thromboembolic event (VTE) is one of the leading causes of maternal deaths in the Western world, with highest risk during the postpartum period. Low-molecular-weight heparin (LMWH) is currently the medicine of choice for the management of acute VTE and for VTE prophylaxis during pregnancy. The aims of the study were to evaluate the maternal and neonatal safety and the efficacy of ...

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Public examination: 5.5.2017

Spectra of linear fractional composition operators and properties of universal operators

Riikka Schroderus

The topics of this thesis in mathematics belong to the area of operator theory which, in general, studies linear transformations between complete normed vector spaces. Here, all operators considered are bounded and act on complex separable infinite-dimensional Hilbert space. A prototypical example of Hilbert spaces is formed by the square summable sequences of complex numbers. Other comm...

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Public examination: 5.5.2017

Bird populations in a changing world: implications for North European conservation

Sara Fraixedas

The combined effects of climate and land-use change constitute a major threat to global biodiversity. Accurate tools to track changes in biodiversity have been largely called upon in order to address global conservation targets. In response to this, a range of ecological indicators have been developed to measure the state of biodiversity in a changing world. Because of their sensitivity ...

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Public examination: 5.5.2017

WATERBIRDS IN A CHANGING WORLD: EFFECTS OF CLIMATE, HABITAT AND CONSERVATION POLICY ON EUROPEAN WATERBIRDS

Diego Pavón Jordán

Climate change has become a major threat for biodiversity in recent decades. Waterbirds, in particular, are very responsive to climate change compared to other avian species and have already shown changes in phenology and distribution. Such strong and rapid response of some species to climate change has motivated debate about the effectiveness of the site-safeguard network, as climate ch...

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Public examination: 5.5.2017

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AGGREGAATTORIT ÄÄNITTEIDEN DIGITAALISESSA JAKELUSSA Tekijänoikeuslainsäädännön ja verotuksen näkökulmasta

Laine, Annina / 27.04.2017

AGGREGAATTORIT ÄÄNITTEIDEN DIGITAALISESSA JAKELUSSA Tekijänoikeuslainsäädännön ja verotuksen näkökulmasta Laine, Annina Tiivistelmä/Referat – Abstract Internet ja digitaalitekniikan kehitys on mullistanut musiikkialaa merkittävästi ja huomattava osa äänitteistä siirtyy nykyään kuuntelijalle digitaalisessa muodossa. Kuluttajille äänitemarkkinoiden digitalisoituminen merkitsee, että mus...

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Kartellivahingon määrän todistaminen vahingonkorvausoikeudenkäynnissä

Korhonen, Sofie / 27.04.2017

Kartellivahingon määrän todistaminen vahingonkorvausoikeudenkäynnissä Korhonen, Sofie Tiedekunta/Osasto Fakultet/Sektion – Faculty Oikeustieteellinen tiedekunta Laitos/Institution– Department Tekijä/Författare – Author Sofie Korhonen Työn nimi / Arbetets titel – Title Kartellivahingon määrän todistaminen vahingonkorvausoikeudenkäynnissä Oppiaine /Läroämne – Subject Oikeustalo...

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The Patent Economics of Synthetic Biology

Bützow, Alexander / 27.04.2017

The Patent Economics of Synthetic Biology Bützow, Alexander Kyseinen työ tutkii uutta bioteknologian muotoa, synteettistä biologiaa, ja sen suhdetta eurooppalaiseen immateriaalioikeuteen, erityisesti patenttioikeuteen. Tutkielman keskeiset kysymykset koskevat sen selvittämisestä, onko 1) synteettisen biologian keksinnöt systeemisesti soveltumattomia nykyiseen patenttioikeuteen, ja 2...

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Vastuun rajoittaminen asianajotoimeksiantosopimukseen perustuvan vastuunhallinnan keinona

Sotamaa, Rasmus / 27.04.2017

Vastuun rajoittaminen asianajotoimeksiantosopimukseen perustuvan vastuunhallinnan keinona Sotamaa, Rasmus Asianajajan mahdollisuuksiin rajata vastuutaan on perinteisesti suhtauduttu varovaisen torjuvasti niin Suomessa kuin muissakin Pohjoismaissa. Torjuvan suhtautumisen perusteet on usein liitetty asianajotoiminnan erityiseen luonteeseen. Vastuunrajoitukset on nähty erityisesti asianaja...

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