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Takotsubo cardiomyopathy? Differentiation from acute coronary syndrome by electrocardiography and biochemistry

Olavi Parkkonen

Takotsubo cardiomyopathy (TTC) is an acute cardiac condition resembling in symptoms acute coronary syndrome (ACS), but without obstructive coronary artery disease. TTC develops almost solely in post-menopausal women and usually after preceding stress. Of all patients with ACS symptoms, TTC incidence is 2%. Due to similar symptoms and findings, differential diagnosis requires coronary ang...

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Public examination: 18.8.2017

Mechanisms of ion beam modification of nanowires and nanotubes

Wei Ren

Nanowires (NWs) and nanotubes (NTs) are considered to be of great importance for future nanotechnology applications, due to the roles of dimensionality and small system size. Potential applications of NWs and NTs range from field-effect transistors to biological applications. However, the one-dimensional (1D) nanostructures and most of their applications are still in an early stage of te...

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Public examination: 18.8.2017

Psychosocial work characteristics, recovery, and health-related outcomes in teaching

Kia Gluschkoff

Occupational stress in teaching concerns not only teachers; it also impacts on wider social contexts. It may negatively affect teachers’ health, but also indirectly influence students’ health and their academic achievements. Yet, despite the challenges teacher stress and health problems pose for society, little research has examined and compared the relevance of different psychosocial wo...

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Public examination: 18.8.2017

Young people's everyday lives in the city: living and experiencing daily places

Heli Ponto

This study, positioned in the fields of humanistic geography and young people’s geographies, deals with young people’s place experiences in the city. I consider such experiences subjective, and study place from the perspective of personal relations and experienced insideness and outsideness. I also understand place as an intersubjective experience comprising social encounters. My researc...

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Public examination: 18.8.2017

Climate, trees and agricultural practices: Implications for food security in the semi-arid zone of Sudan

Mustafa Fahmi

Livelihoods are precarious in arid and semi-arid regions, such as Sudan, as the main food crops are often grown in production systems that heavily depend on climatic conditions and appear to be threatened by several factors. Over 70% of Sudanese are farmers who rely mainly on rain-fed agriculture to secure their livelihoods. Their crop cultivation is constrained by such factors as climat...

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Public examination: 18.8.2017

Postmitotic state of a cell as a challenge for regeneration: inner ear as a model

Maarja Laos

Supporting cells (SCs) of the mammalian inner ear are differentiated, postmitotic cells that hold promise as a platform in therapeutic interventions to replace lost sensory cells, the hair cells (HCs). However, SCs exhibit an age-dependent decline in their responsiveness to regenerative manipulations that aim to trigger cell cycle re-activation or to stimulate transdifferentiation into H...

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Public examination: 18.8.2017

Molecular genetics of rare puberty disorders in Finland and Denmark

Johanna Känsäkoski

Sexual differentiation and pubertal development are complex processes whose disruption leads to the abnormal development of primary and/or secondary sexual characteristics. Although mutations in several genes have been implicated in these disorders, the majority of the patients still lack a molecular genetic diagnosis. The aim of this thesis work was to identify genetic defects underlyin...

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Public examination: 18.8.2017

Black holes, stability and geodesics in modified gravity theories

Hannu Nyrhinen

For a hundred years Einstein's general relativity (GR) has persisted as the standard model of gravity. To date, no observations conflict it. Moreover, GR has predicted effects that have been later confirmed, such as the deflection of light, the redshift of light in gravitational field, and gravitational waves. Modifications to GR have been studied since the early days of relativistic...

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Public examination: 22.8.2017

Projected climate change impact on fire risk and heavy snow loads in the Finnish forests

Ilari Lehtonen

The aim of this work was to study the climate change impact on two specific abiotic risks affecting forests in Finland: fires and heavy snow loads. Approximately 1000 forest fires occur annually in Finland, but thanks to effective fire suppression, the average size of fires is only about 0.5 ha. Occasionally, heavy snow loading causes forest damage, which reduces stand quality in boreal ...

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Public examination: 22.8.2017

Socioeconomic and -demographic determinants of myocardial infarction incidence and survival - A longitudinal register-based study of Finnish men and women

Fanny Kilpi

Social inequalities in coronary heart disease (CHD) are a notable feature of modern societies, and create a major population health burden. Though CHD incidence and mortality have been in decline in past decades, the absolute and relative inequalities by socioeconomic position (SEP) remain substantial. This thesis investigates the influence of different social determinants on MI incidenc...

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Public examination: 24.8.2017

Trimeric autotransporters and their ligands - structural studies

Kornelia Mikula

During host invasion, pathogenic bacteria express a variety of virulence factors that facilitate their escape from the immune system and thus enable propagation of the infection. The trimeric autotransporter adhesins (TAAs) are one example of a specialised virulence factors expressed by many Gram- negative bacteria, such as Yersinia spp, Escherichia coli, Moraxella catarrhalis, and other...

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Public examination: 25.8.2017

Effectiveness of economic policy: Assessment based on nonnormalities

Päivi Puonti

This dissertation is a collection of three self-contained essays that analyse the effects of monetary and fiscal policy using novel time series econometric methods. The research questions become important both academically and for practical policy-making after the global financial crisis of the early 2000s. The main contribution of the dissertation is in applying recent time series econo...

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Public examination: 25.8.2017

Scots pine (Pinus sylvestris L.) heartwood formation and wounding stress: A view from the transcriptome

Kean-Jin Lim

Scots pine is an ecologically and economically important tree species in Finland because of its heartwood (HW) quality traits that contributed by the pine HW extractives, which is mainly attributed to stilbenes. Pine stilbenes, pinosylvin (PS) and its monomethyl ether, are development and stress inducible metabolites. During HW formation, biosynthesis of pine stilbene takes place in a na...

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Public examination: 25.8.2017

Diet Quality and Its Association with Gestational Diabetes Mellitus

Jelena Meinilä

Gestational diabetes mellitus (GDM) is increasing globally and it causes pregnancy complications and later type 2 diabetes (T2D) for the mother and offspring. Studies of the association between diet in Nordic populations and GDM, as well as the effect of observed dietary change on the risk is scanty. The thesis was based on data from the Finnish Gestational Diabetes Prevention Study RADI...

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Public examination: 25.8.2017

Elämän päätösjakson haaste : ALS-tautiin sairastuneen eksistentiaalinen prosessi ja uskonnollinen spiritualiteetti

Matti-Pekka Virtaniemi

Jotkut vakavasti sairastuneet saattavat kokea elämänsä laadullisesti hyväksi, jopa hyvin arvokkaaksi elämänvaiheeksi. Tämän odottamattoman asian selvittämiseksi haastateltiin kuutta ALSiin sairastunutta henkilöä, jokaista kolme kertaa yhden vuoden aikana. ALS-tauti on parantumaton, etenevä, liikehermot tuhoava ja muutamassa vuodessa kuolemaan johtava neurologinen sairaus. Tutkimuksen tar...

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Public examination: 25.8.2017

Wind gusts in the atmospheric boundary layer

Irene Suomi

Wind gusts, which are short duration (typically 3 s) wind speed maxima, are representative of the extreme wind conditions. They are very important for human activity, because the strongest gusts associated with storms are the most significant single cause of natural hazards. The impact of wind gusts on different structures depends on the characteristics of each structure. For example for...

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Public examination: 25.8.2017

Laboratory Monitoring of Direct Oral Anticoagulants

Tuukka Helin

Direct oral anticoagulants (DOACs), the thrombin inhibitor dabigatran and the anti-Xa inhibitors rivaroxaban and apixaban are are simple to use as standard dosing is recommended and no routine monitoring of coagulation is advocated. However, in certain clinical situations, e.g. acute thrombosis or bleeding, emergency surgery and renal or hepatic failure, assessing anticoagulant bioactivi...

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Public examination: 25.8.2017

“People who don’t live what we live, don’t understand” : Youths’ experiences of hypermobility

Saija Benjamin

This qualitative PhD study examines the lived experiences of eight young individuals who moved from one country to another several times during their childhood because of their parents’ profession, hence the term hypermobility in the title. As international, work-based mobility is increasing, it is of critical importance to observe how it affects childhood in general and how the children...

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Public examination: 25.8.2017

"They Come from Above" - Exploring Finnish Development Cooperation in the Field of Meteorology, 1968-2015

Minna Mayer

Finnish development cooperation in the field of meteorology has continued for nearly 50 years and over 100 countries have been beneficiaries of this aid. Cooperation in this field is complex, it brings together public and private sector actors and experts from different backgrounds. Projects have succeeded in capacity development, but have struggled with sustainability. Local capacity of...

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Public examination: 26.8.2017

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AGGREGAATTORIT ÄÄNITTEIDEN DIGITAALISESSA JAKELUSSA Tekijänoikeuslainsäädännön ja verotuksen näkökulmasta

Laine, Annina / 27.04.2017

AGGREGAATTORIT ÄÄNITTEIDEN DIGITAALISESSA JAKELUSSA Tekijänoikeuslainsäädännön ja verotuksen näkökulmasta Laine, Annina Tiivistelmä/Referat – Abstract Internet ja digitaalitekniikan kehitys on mullistanut musiikkialaa merkittävästi ja huomattava osa äänitteistä siirtyy nykyään kuuntelijalle digitaalisessa muodossa. Kuluttajille äänitemarkkinoiden digitalisoituminen merkitsee, että mus...

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Kartellivahingon määrän todistaminen vahingonkorvausoikeudenkäynnissä

Korhonen, Sofie / 27.04.2017

Kartellivahingon määrän todistaminen vahingonkorvausoikeudenkäynnissä Korhonen, Sofie Tiedekunta/Osasto Fakultet/Sektion – Faculty Oikeustieteellinen tiedekunta Laitos/Institution– Department Tekijä/Författare – Author Sofie Korhonen Työn nimi / Arbetets titel – Title Kartellivahingon määrän todistaminen vahingonkorvausoikeudenkäynnissä Oppiaine /Läroämne – Subject Oikeustalo...

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The Patent Economics of Synthetic Biology

Bützow, Alexander / 27.04.2017

The Patent Economics of Synthetic Biology Bützow, Alexander Kyseinen työ tutkii uutta bioteknologian muotoa, synteettistä biologiaa, ja sen suhdetta eurooppalaiseen immateriaalioikeuteen, erityisesti patenttioikeuteen. Tutkielman keskeiset kysymykset koskevat sen selvittämisestä, onko 1) synteettisen biologian keksinnöt systeemisesti soveltumattomia nykyiseen patenttioikeuteen, ja 2...

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Vastuun rajoittaminen asianajotoimeksiantosopimukseen perustuvan vastuunhallinnan keinona

Sotamaa, Rasmus / 27.04.2017

Vastuun rajoittaminen asianajotoimeksiantosopimukseen perustuvan vastuunhallinnan keinona Sotamaa, Rasmus Asianajajan mahdollisuuksiin rajata vastuutaan on perinteisesti suhtauduttu varovaisen torjuvasti niin Suomessa kuin muissakin Pohjoismaissa. Torjuvan suhtautumisen perusteet on usein liitetty asianajotoiminnan erityiseen luonteeseen. Vastuunrajoitukset on nähty erityisesti asianaja...

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