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Browsing by discipline "Psykologi"

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  • Häkkinen, Marie (2019)
    The idea that fandom is connected to maladaptive development or cognitive deficits seems to underlie psychological studies on celebrity adoration. These studies often describe fandom as celebrity worship and offer hypotheses that seem to be at least in part based on stereotypes. I review the psychological study of fandom that is based on the idea of three types of celebrity adoration between which the adoration ranges from what is perceived as harmless to such that can be described as pathological. I review results that both support and contradict the suggested model and finally, ask if celebrity adoration should be perceived as a personality based coping mechanism rather than a maladaptive state. Celebrity adoration would seem to entail both a cognitive component and lower psychological well-being. In addition, both personality and personality based coping mechanisms are associated with celebrity adoration. I suggest that one explanation to celebrity adoration could be found from personality and psychological well-being. In this context celebrity adoration could be understood as a personality based coping mechanism that is facilitated by stress-related cognitive deficits.
  • Lehtola, Emma (2020)
    Aims. Previously psychopathy has been regarded as a homogenous and categorical personality disorder that cannot be treated. However, recent findings have suggested that psychopathy may be both a heterogenous and dimensional phenomenon. Several studies have found at least two subtypes, out of which primary and secondary psychopathy are the most prevalent. These two subtypes seem to manifest on their own, partly overlapping dimensions. The aim of this review was to evaluate the reliability of the evidence on heterogeneity of psychopathy and the model of two different subtypes, the core traits of psychopathy, and the differences in traits and etiology between the subtypes. Methods. The review is based on literature found from the Google Scholar database by searching for the term ”psychopathy” in connection with the words ”subtypes”, ”primary”, ” secondary”, ”heterogeneity”, ”variants” and ”treatment”. Conclusions. The evidence on the heterogeneity of psychopathy and the model of two different subtypes is strong. The reviewed studies suggest that callousness and lack of empathy are the core traits of psychopathy. Additional core traits of the primary subtype were low negative affect, high positive affect, few internalizing symptoms, higher control and high trait boldness and fearlessness. The distinctive traits of the secondary subtype were high negative affect, low positive affect, high impulsivity, lack of self-control, high internalizing symptoms and neuroticism. As both subtypes seem to have very distinct traits, the treatability of psychopathy may depend on the subtype which should be taken into consideration when developing and researching treatment methods. Research on psychopathy has mostly been conducted on samples of Western white men and therefore it is uncertain if psychopathy manifests in a similar way in different populations. Hence psychopathy and its subtypes require more research on differing populations.
  • Salo, Verna (2016)
    Objectives. Bipolar disorder is a mood disorder in which the mood varies between depressive state and mania or hypomania. In earlier studies it has been observed that the depressive episode of bipolar disorder might be often inaccurately diagnosed as recurrent depression or unipolar depression. This might lead to lengthening of the symptoms and at worst, to use of antidepressants without the simultaneous use of mood stabilizers which in turn might lead to mania or hypomania. Thus, the objective of this review is to study the distinctive factors of the depressive episodes between bipolar disorder type I and II and unipolar depression, emphasizing genetic factors, the symptoms during depressive episodes, comorbid disorders, subthreshold hypomanic symptoms and the effects of pharmacotherapy during the depressive episodes. Results and conclusions. In the review it was found that many factors distinguished the depressive episodes of bipolar disorder and unipolar depression although for comorbid disorders, especially for alcohol and substance dependence and abuse, the number of depressive episodes, and the severity of depressive symptoms the evidence was contradictory. The family history of bipolar disorder, the depressive symptoms and the age at the onset of the mood disorder were found to be associated with the onset of bipolar disorder. The use of antidepressants in bipolar disorder without the simultaneous use of mood stabilizers was noted to possibly lead to a switch from depression to mania or hypomania. Bipolar disorder was also found to share genetic factors with depression and schizophrenia which supports the idea that mood disorders constitute a dimension. In the future, it would be important to increase the accuracy of diagnostics and diagnostic criteria should be re-evaluated. Moreover, the caregivers should be educated about the differences between the depressive episodes in bipolar disorder and unipolar depression and the assessment of family history of bipolar disorder should be established as a basic procedure in the assessment of a mood disorder. Also, one should pay more attention to the occurrence of subthreshold hypomanic symptoms and the use of pharmacotherapy and its effects on the individual during the treatment of a depressive episode. It would also be important to develop a pharmacological treatment that could be used in the treatment of both unipolar depression and bipolar depressive episode.
  • Huttunen, Iina (2020)
    Purpose. In today’s society we have a lot of pressure on us and have fast-paced lifestyles. In this hectic goal-oriented life, handicrafts, representing slow living, have gained popularity and attained media attention. However, handicrafts are not acknowledged in scientific fields as well as music and visual arts. The purpose of this thesis is to investigate the relationship between handicrafts and well-being, as well as how handicrafts have been implemented in rehabilitation or therapy of clinical groups comprising different mental health disorders and progressive memory disorders. Methods. The data for this thesis were collected from Google Scholar, Scopus and PubMed. The following keywords were used: knitting, handicrafts, handcrafts, well-being, wellbeing, psycholog*, therapy, stress and anxiety. The Finnish keywords käsityö, psyykkinen hyvinvointi and terapia were also used. Results and conclusions. Since most of the studies in the field are descriptive, we cannot talk about causality but only correlation. Nevertheless, it has been concluded that the handcrafters report handicrafts having many positive effects on their well-being. In addition to the direct mental health benefits, handicrafts seem to have indirect effects on well-being through different kind of cognitive and social phenomena. When it comes to different clinical samples, positive correlation between handicrafts and well-being has also been detected. These results support the hypothesis that handicrafts may have therapeutic effects. Based on the studies conducted so far, it seems justified to use handicrafts in therapy or as a part of therapy or self-care. However, more experimental studies are needed to be able to tell how we can use handicrafts more effectively and for whom it is most suitable.
  • Niemi, Saija (2019)
    Virtual reality displays with a pixel definition which corresponds to that of the human foveal definition cannot be built at present. Therefore, we must develop ways to reduce file sizes of virtual reality contents and to reduce processing demands without lessening the user experience. Virtual reality contents can be foveated, for example, by gaze-contingently peripherally blurring the image. This approach takes advantage of the fact that human visual acuity diminishes from central vision to peripheral vision. Usually, the level of foveation has been chosen according to its visibility or subjective obtrusiveness. Peripheral gaze-contingent blurring can, however, alter eye movement behaviour and performance on tasks. In this review, I examined the literature on foveated virtual reality, the effects of peripheral gaze-contingent blurring and their implications on foveated virtual reality. The aim was to find possible criteria for an adequate level of foveation. The literature used was peer-reviewed experiments and reviews searched on Scopus database. In addition, articles were included from the citations of the chosen articles. Keywords related to the articles used were foveated virtual reality, visual acuity and contrast sensitivity in the peripheral vision and effects of gaze-contingent blurring on eye movements and task-performance. User research on foveated virtual reality was scarce. The adequate level of foveation can be chosen according to its perceptibility, alteration on eye movements or alteration on task-performance. Perceptually-based foveation can be constructed from human visual acuity and contrast sensitivity function. However, peripheral gaze-contingent blurring can shorten saccade lengths, increase fixation times and impair visual search performance. These effects arise before blurring is perceptible. Consequently, if unchanged eye movement parameters and unimpaired search performance are used as a criterion for foveation, peripheral filtering will be weaker and therefore its gains will also be weaker. Moderate peripheral blurring might not deteriorate performance on other tasks that, for example, require expertise. Because the effects of peripheral blurring depend on the task and the qualities of the user, foveation could be adjusted separately for different virtual reality contents and users.
  • Marin, Pinja (2016)
    Attention-Deficit Hyperactivity Disorder (ADHD) has been associated with increased criminality in both clinical and population-based studies. However, the details of and the mechanisms behind ADHD’s connection to increased criminality are not well-known yet. This is understandable considering the complex nature of the association between ADHD and criminality. In the first chapter of this paper the role of Conduct Disorder in the association between ADHD and criminality will be reviewed. Then, the connection of the two symptom dimensions of ADHD (attention-deficit and hyperactivity-impulsivity) to the association between ADHD and criminality will be discussed. In general, ADHD with comorbid Conduct Disorder has been linked to more severe and frequent delinquency compared to uncomplicated ADHD-diagnosis. Children with ADHD have an increased risk of Conduct Disorder compared to the general population. Especially hyperactivity-impulsivity has been connected to the occurrence of comorbid Conduct Disorder. ADHD’s association with Conduct Disorder has been explained with the overlap of the two disorders as well as causally with the symptoms of ADHD possibly predisposing to Conduct Disorder. Attempts to control the effects of comorbid Conduct Disorder has lead to different results regarding the independent association between ADHD and criminality. After controlling for comorbid mental disorders the symptoms of ADHD have been suggested to predispose individuals to less serious and specific types of crimes. The associations of hyperactivity-impulsivity and attentional problems with criminality have also been studied separately. In most studies hyperactivity-impulsivity has been more strongly associated with criminality than attention-deficits. Research regarding the relation of Conduct Disorder and the symptom dimensions of ADHD with the association between ADHD and criminality are partly conflicting. Researching the connection between ADHD and criminality further would be important to be able to settle these conflicts. It would also give psychologists better tools to help individuals with ADHD who could be prone to committing criminal acts.
  • Heinonen, Helmi (2017)
    In this thesis I study special features related to the mental health of the people with intellectual disabilities and focuse on the mental health risks related to intellectual disability. I view disability from the perspective of International Classification of Functioning, Disability and Health (ICF). This biopsychosocial model combines both the medical perspective and the perspective of the disability studies. Mental health risks related to intellectual disability can be divided into two categories: biological and cognitive factors, and social and societal factors. The conclusion of the thesis is that intellectual disability as a deviance of the development of the neural system sets an individual into different position than a person without disabilities according to mental health risks, and that social and societal risk factors continue increasing the risk to mental health problems significantly. Participation restrictions and the social stigma of the intellectual disability are themes that stand out from the social and societal factors. Discussion of the thesis considers options how to have an influence on the social and societal risk factors. Thesis suggests that the most important tool to prevent the mental health problems of the people with intellectual disabilities would be to have as inclusive society as possible.
  • Malkki, Veera (2018)
    Psychosomatic symptoms cause psychological and physiological distress for many individuals. They weaken person’s ability to take part in social interactions and act as a part of their society. Usually somatic symptom disorders are treated by primary care physician, but there is no specific cure for them. Trustworthy and stable relationship between doctor and patient is an important factor of the treatment. People who suffer from psychosomatic symptoms pay great attention to their bodily messages, and this often cause them feelings of distress. The aim of this thesis was to study, what kind of effects has been found in using body oriented interventions in treatment of somatic symptom disorders. Included interventions were mindfullness-, yoga-, and relaxation based interventions, and body awareness psychotherapy. According to the research data available, it seems that body oriented interventions could reduce symptoms of depression and anxiety, and improve the overall quality of life, for those who suffer from somatic symptom disorders. However, more studies are needed, before certain conclusions can be made.
  • Seppälä, Maaria (2016)
    In psychological assessment projective techniques have been a target of criticism mainly because they are not considered as a valid and reliable methods in scientific study. When projective techniques are used in psychological decision making they should also be incremental valid. Incremental validity is found when an instrument contributes important and additional information above and beyond other used instruments. In Finland the most popular projective test is Wartegg Zeichen Test (WZT) where the tested person should complete eight different drawings. Nowadays psychologist use Gradziella’s interpretation system for WZT altough it is considered unreliable and unscientific. Alexithymic persons tend to draw less human face in WZT, yet more study is needed before any conclusions can be drawn. Moreover, research traditions of WZT are vague. Scientifically we cannot say that WZT has validity, reliability nor incremental validity, because we do not have enough scientific evidence. Incremental validity of WZT should be studied more and the usefullness of WZT should be reconsidered. In addition, there should be new updated finnish normal sample and even an all new interpretation system based on scientific study for WZT.
  • Jaurimaa, Janessa (2018)
    The purpose of this review was to examine the association between language skills and emotion regulation in preschool children. The association has been shown with several different methods, three of which were reviewed here. First, studies have shown that difficulties and delays in language development often co-occur with emotional difficulties and conduct disorders. Second, inner speech can be used in guiding one's thoughts and actions and third, conversation-based interventions can affect emotional competence including regulation skills. In addition, it was examined which aspects of language are most significant in regard to emotion regulation and it was also considered what might be the mediating mechanisms between language and emotion regulation in light of current research. Children with specific language impairment were twice as likely to have emotional difficulties relative to typically developed children and difficulties were more frequently clinical or disorder level. Children with better language skills used more internalized private speech. Using more internalized private speech was associated with less anger expression and made it possible for those children to use better regulation strategies. Conversation-based interventions had an effect to children's emotional competence including regulation skills and prosocial behaviour. Studies showed that vocabulary size was a significant predictor of regulation skills.
  • Varjola, Julia (2017)
    Bilingualism has been proposed to practice general executive functions. The hypothesis is based on the assumption that using two languages takes advantage of some of the same processes as general executive functions. The objective of this thesis was to describe by means of literature review the present knowledge about the connection between language switching and switching that is under general executive functions. The review considered whether language switching is based on the same processes as general executive functions and whether the amount of language switching is related to executive functions. The review was limited to behavioral studies. The overlap of processes used in language switching and general executive functions has been studied by comparing the efficiency of switching in a task measuring language switching and a task measuring the switching component of executive functions. The results of the literature review were not consistent. In some studies, the results indicate that language switching and the switching component of general executive functions share processes whereas other studies did not find a connection. It is possible that age of language acquisition and level of fluency may affect the overlap between these processes. The connection between the amount of language switching and general executive functions has been studied by measuring the amount of language switching in everyday life and looking at its connection to the efficiency of switching in a task measuring the switching component of executive functions. The results of the review are conflicting. Nevertheless, most studies indicate that the overall amount of everyday language switching does not seem to be related to the switching component of executive functions. Some studies, however, suggest that if the quality of language switching and cognitive load is taken into account a connection to the switching component of executive functions can be observed.
  • Minkkinen, Hanna (2020)
    Pain is a common symptom among cancer patients, and its occurrence may result from cancer itself, cancer treatment and/or other non-cancer health problems. Cancer pain is usually treated medically. After the development of the biopsychosocial model of pain it was understood that psychological factors affect the pain experience. Nonpharmacologic interventions are generally the basis of pain management, and psychological interventions significantly contributes to the management of cancer pain. This review examines evidence for psychological interventions that can be used to reveal adults’ cancer pain. The literature search was conducted in one database, PubMed, and the search was limited to years 2010-2019. The search was made using two keyword combinations: 1) psycholog* and oncological pain, and 2) psychological intervention and oncological pain. Articles were chosen by reviewing titles and abstracts. In addition, reference lists of the chosen articles were reviewed to identify additional relevant articles. Articles addressing examination or operation related pain were excluded as well as studies that included children or adolescents. Psychological interventions used in cancer pain management can be divided into skill based and education-based interventions. In skill-based interventions the patient learns concrete coping strategies. In addition, they aim at changing the way the patient interprets pain. In education based interventions the patient acquires information about the disease, analgesic medications, and effective communication regarding pain with health care providers. According to meta-analyses psychological interventions were effective in managing cancer pain. They affected both pain severity and inconvenience. Studies focusing only one intervention type showed partially similar results. Mindfulness-based programs were the most promising of the skill-based interventions. The evidence for hypnosis and yoga was weak, so more research is needed before any clear conclusions can be made. All education-based interventions were effective in managing cancer pain. Thus, pain education seems to be beneficial regardless the way it is implemented.
  • Kärhä, Tuomas (2020)
    Skitsofrenia on pitkäkestoinen psykoottinen häiriö, johon kuuluu kognitiivisen toimintakyvyn laskua. Kognitiivisten oireiden on havaittu olevan yhteydessä skitsofreniapotilaiden arjen toimintakykyyn ja koettuun elämänlaatuun. Kognitiivinen remediaatioterapia on interventiomuoto, jonka tavoitteena on kuntouttaa potilaan kognitiivista toimintakykyä kognitiivisten tehtävien ja strategiaharjoittelun avulla. Tämän katsauksen tavoitteena on antaa yleinen kuva kognitiivisesta toimintakyvystä skitsofreniassa sekä kognitiivisen remediaatioterapian sisällöstä ja tehokkuudesta. Katsauksen aineisto etsittiin PubMed- ja PsycINFO- tietokannoista. Sisällytetyt tutkimukset ja katsaukset valittiin relevanssin, julkaisupäivämäärän ja laadukkuuden mukaan. Uudempia tutkimuksia suosittiin, mutta myös vanhemmat, korkealaatuiset tutkimukset huomioitiin. Kognitiivinen remediaatioterapia on tutkitusti tehokas keino skitsofreniapotilaiden kognitiivisen ja funktionaalisen toimintakyvyn kuntouttamiseen. Sen hyödyt ovat korostuneita etenkin silloin, kun CRT-interventio on yhdistetty tavanomaiseen psykiatriseen kuntoutukseen. Lisätutkimusta tarvitaan muun muassa CRT:n taustalla vaikuttavien mekanismien ymmärtämiseksi.
  • Juntunen, Heidi (2017)
    Chronic pain is a disabling condition with remarkable economic costs and great resistance to treatment. Therefore, it is important to find new methods to recognize patients with high risk of developing chronic pain and to prevent the transition to chronicity. The purpose of this review is to present and evaluate the evidence of cognitive–behavioral interventions as preventive care for chronic pain. The fear–avoidance model of pain suggests that a minority of people with acute pain develop a persistent disability through avoidance behavior thriven by cognitive factors such as pain catastrophizing, fear of movement and false fear–avoidance beliefs. Indeed, psychological factors have been shown to predict the development of chronic pain even better than biomedical factors. Cognitive–behavioral interventions targeting these risk factors appear to be useful in preventing chronic pain and especially in pain-related work absenteeism. It is however unclear whether the positive effects of cognitive–behavioral interventions are mediated through the change in psychological risk factors or rather some other factors, such as therapeutic rapport or peer support that positively affect commitment to treatment. It is important to develop standardized treatment protocols in the future. The effect of intervention timing and the level of psychological risk on the preventive efficacy of cognitive–behavioral interventions should also be further studied. Developing more accurate screening tools to recognize patients with elevated risk of chronic pain in primary care is also crucial for efficient preventive care of pain conditions. In addition to work absenteeism, more attention should be paid to the effects of these early interventions on pain symptoms and patients’ quality of life.
  • Talvitie, Emma (2016)
    Study objectives: The efficacy of cognitive behavioural therapy based interventions in treating sexually abused children and adolescence is examined in this meta-analysis . Sexual abuse of minors is a serious issue with severe short and long-term consequences on physical and mental health. Previous reviews have shown cognitive behavioural therapy treatments to be effective in treating sexually abused children and adolescence. This meta-analysis adds latitude to this field of study by including more recent studies that have been excluded from earlier reviews. Methods: In all of the studies included all the participants were under 18, they have been sexually abused and they have received cognitive behavioural therapy treatment. Studies were researched through two different databases using different keywords and references of the previous meta-analyses were checked. 18 studies fitting the criteria were found. For each study one effect size, Cohen’s d, were calculated. In the meta-analysis random effects model were used and studies were weighted by variance. Heterogeneity of the studies was examined with Q-test and publication bias with Funnel plot and Fail -safe N-test. Results and conclusions: Cognitive behavioural therapy based interventions are effective. The average effect size was d=0.67 and it was statistically significant. The included studies were heterogeneous and affected by publication bias. The results support the use of these kinds of interventions in treating sexually abused minors.
  • Ketvel, Laila (2018)
    Abstract Objective. Cognitive flexibility is defined as the ability to properly adjust one’s behaviour to changing environmental demands. Research shows that in many psychiatric illnesses this ability is impaired compared to healthy controls. It is also known that the psychopathology of eating disorders includes rigid ways of functioning that resemble obsessive-compulsive behaviours. Furthermore, eating disorders have proved difficult to treat with traditional psychotherapy, which is thought to reflect the incapability to change one’s behaviour according to feedback. It has been proposed that eating disorder patients have poor cognitive flexibility, and this manifests in the symptoms and makes these mental illnesses difficult to treat. The purpose of this review is to examine the incidence of problems in cognitive flexibility tasks in eating disorder patients. Other research questions include the neural correlates of these problems, the direction of the causal relationship between cognitive rigidity and eating disorders, and the effectiveness of cognitive remediation therapy in eating disorder treatment. Methods. A search using the term ”eating disorders” in connection with the words ”cognitive flexibility”, ”set shifting”, ”neuropsychology”, ”neural correlates”, ”executive function” and ”cognitive remediation” was made using electronic databases. The databases used were Google Scholar, PubMed, Helka, Cochrane Library and PsychInfo. Results and conclusions. A considerable amount of evidence showed that eating disorder patients have difficulties in cognitive flexibility compared to healthy controls. This has been proposed as an explanation for the poor outcomes of eating disorder treatments. The neural functions of eating disorder patients also differed from those of healthy controls while performing cognitive flexibility tasks, which is thought to reflect the problem in cognitive processing and explain the lower than average scores. There are different theories regarding the direction of the causation between cognitive rigidity and the development of eating disorder pathology: some researchers think that problems in cognitive flexibility cause eating disorders, while others argue that the malnutrition associated with eating disorders precedes the cognitive deficit. Both theories had empirical support, and it seems that the process might be two-directional. There have been efforts to include cognitive remediation in the treatment of eating disorders in order to ameliorate both the cognitive deficit and the eating disorder symptoms. Research on the topic is still quite limited, but the initial results about combining traditional therapy with cognitive treatment seemed promising.
  • Kujanpää, Riina (2017)
    Objectives: Schizophrenia and other psychotic disorders are serious mental illnesses characterized by positive, negative and disorganized symptoms. In addition to the aforementioned symptom types, psychotic disorders are associated with a wide array of cognitive deficits. Cognitive functioning has been found to deteriorate already during the prodromal phase preceding the onset of a psychotic disorder. In schizophrenia, the level of severity of cognitive deficits has been found to become settled fairly quickly after the onset of illness. During the last few decades, a form of neuropsychological rehabilitation called cognitive remediation therapy has been developed for the alleviation of cognitive deficits associated with psychotic disorders. The aim of this review is to examine whether cognitive remediation therapy is an effective form of rehabilitation for people at risk for psychosis, patients with first episode psychosis and patients in the early course of schizophrenia or other psychotic disorders. The effectiveness of cognitive remediation therapy is evaluated in terms of its capabilities to alleviate cognitive deficits and enhance functioning. Methods: The material for this review consists of research articles retrieved from Scopus. The article searches were conducted using various combinations of the following search terms: cognitive remediation, schizophrenia, psychosis, first episode, early course, high risk, prodrom* and premorbid. Two systematic reviews, one combined meta-analysis and systematic review and three original research reports were included in this review. Results: Cognitive remediation therapy has been shown to enhance the cognitive functioning of patients in the early course of psychotic disorders and patients with recent onset psychosis. Positive effects on patients’ functioning have also been found, and alleviation of other symptoms of psychotic disorders due to cognitive remediation therapy has been reported in some studies. Few studies have examined the effectiveness of cognitive remediation therapy for people at risk for psychosis, but current evidence tentatively suggests that this population could also benefit from the treatment. Future studies should investigate how different kinds of cognitive remediation therapy affect different aspects of cognition and functioning, what kinds of factors explain the effects of the treatment and how cognitive remediation therapy could be tailored to the needs of different groups and individuals.
  • Ääpälä, Jarno (2017)
    There are two types of assumed brain related reserves. Brain reserve is associated with structural qualities and cognitive reserve (CR) is associated with brain functioning. Both reserves prevent deterioration of cognitive abilities when brain suffer structural damage due to, for example, memory disorders. CR is defined by brain functioning that differs from what would be predicted from brain structure. This bachelor’s thesis is about measuring CR. Measurement of CR was studied in publications that were published in 2012 and after that. Studies were selected on basis of describing different methods of measuring CR and that had gained lot of attention. CR or brain pathology that CR is related to is not possible to measure directly. Research on CR is still young and measuring methods develop rapidly. In early days of CR research single measurement items that were thought to be best predictors of CR were used and they were called proxies. By the year 2006 most widely used CR proxies were education, profession, mental activities and premorbid intelligence. CR can also be measured with several indicators. Using several indicators has become more common in recent years. There are several ways to use more than one indicator. The right way cannot be defined empirically because they are statistically identical. Recent research have found bilingualism to be proxy of CR. This indicates that bilingualism has effect on CR, which indicates that CR can be modified with interventions for example. It means that studies should use formative measurement model that has CR as latent variable that is estimated with proxies using factor analysis or principal component analysis. It seems that it’s possible to modify CR and larger CR protects against cognitive impairment caused by Alzheimer’s disease. This will probably be incentive to create interventions to risk groups. Most studies about CR have not controlled brain structure, for example brain size which has effect on CR but cannot be modified with interventions. More research where brain reserve is controlled is needed for being able to predict the effect of possible preventions that are being developed.
  • Kekkonen, Niko (2020)
    Tavoitteet. Väestön ikääntymisen myötä monet sairaudet, mukaan lukien muistisairaudet tulevat lisääntymään. Alzheimerin tauti on merkittävin dementiaa aiheuttava sairaus, johon riski sairastua kasvaa voimakkaasti iän myötä. Väestön ikääntyminen asettaa haasteita Alzheimerin taudin interventio-, diagnoosi- ja hoitomenetelmille. Ymmärrys sairauden riskitekijöistä ja suojaavista tekijöistä sekä sen etenemisestä niin neuropatologian kuin kliinisen oireiston suhteen auttaa tuleviin haasteisiin vastaamisessa. Kognitiivisen reservin teoria lisää osaltaan tätä ymmärrystä, toisaalta sairastumisriskiä pienentävistä tekijöistä, toisaalta sairauden neuropatologian ja kliinisen ilmentymisen välisestä suhteesta. Kognitiivisen reservin tiedetään antavan yksilölle suojaa Alzheimerin taudin dementiaoireita vastaan ja hidastavan toimintakyvyn laskua. Tämän katsauksen tavoitteena oli selvittää, voiko kognitiivinen reservi suojata yksilöä myös Alzheimerin taudin patologian kehittymiseltä. Menetelmät. Kirjallisuushaku suoritettiin käyttämällä Helka, PubMed ja Scopus tietokantoja. Hakutermeinä käytettiin Cognitive reserve AND Alzheimer’s disease, Alzheimer’s disease biomarkers, Alzheimer’s disease pathology ja Cognitive reserve measurement. Varhaisella iällä (<65v) alkavaa Alzheimerin tautia koskevat tutkimukset jätettiin huomiotta. Muita ehtoja tutkimusajankohdan tai -menetelmien suhteen ei asetettu. Tutkimuskysymyksen kannalta katsaukseen löytyi neljä ’ydintutkimusta’, joista kolme käsitteli kognitiivisen reservin yhteyttä Alzheimerin taudin keskeisimpien biomarkkereiden kehittymiseen. Yksi tutkimuksista käsitteli Alzheimerin taudin tunnetuimman geneettisen riskitekijän, apolipoproteiini E4 alleelin vaikutusta yksilön koulutustaustan ja hippokampuksen rakenteen väliseen suhteeseen. Tulokset ja johtopäätökset. Kognitiivisen reservin ja alzheimerin taudin biomarkkereiden välistä yhteyttä käsitelleet tutkimukset antavat viitteitä siitä, että korkeampi reservi saattaa ehkäistä Beta-amyloidiplakkien muodostumista aivoihin. Tutkimukset sisälsivät tiettyjä rajoitteita, ja olemassa olevat tulokset perustuvat yksittäisiin mittareihin ja pieneen määrään koehenkilöitä. Aiheesta tarvitaan lisää pitkittäistutkimusta. APOE4 alleelin vaikutusta koulutuksen ja hippokampuksen rakenteen väliseen yhteyteen selvittänyt tutkimus osoitti, että riskigeenin kantajilla mediaalisen ohimolohkon tiettyjen alueiden kortikaalinen paksuus lisääntyi suhteessa opiskeluvuosien määrään. Vastaavaa ei havaittu matalan riskin ryhmässä. Havainto kaipaa lisätutkimusta.
  • Viitaharju, Janika (2017)
    In this overview answers are looked for three questions: how well do cognitive ability tests predict work performance and do the results generalise to different countries, is there differences in the pre-dictive validity of cognitive ability tests between different jobs, and which is better predictor for work performance, general mental ability or specific cognitive ability tests. Both general mental ability and specific cognitive abilities are good predictors for work performance and results generalise to different countries. There were moderators for the association between gen-eral mental ability and work performance. Job complexity and publishing year of the research were moderators. Publishing year was moderator also for the association between specific cognitive abil-ity tests and work performance. There were no differences in the predictive validity of specific cog-nitive ability tests between different jobs. General mental ability was a better predictor for work per-formance than specific cognitive ability tests. The predictive validity of ability tests has been studied only in western countries so in the future it would be important to study do the result generalise also to different cultures. In addition it would be important to also study more the moderating effect of the year of publication. Is there really such an effect and if there is then it would be important to study why.