Browsing by Author "Sipilä, Katariina"

Infants´ and children´s diet influences normal development and overall health. A balanced diet providing essential nutrients is crucial. Recent research has examined the dietary patterns of children and infants, exploring potential associations between food components and the emergence of illnesses. Notably, investigations into relationships between dietary factors and metabolite have gained prominence. Metabolomics offers a means to investigate individual´s nutrition, health status, illnesses, and the interaction of medications and contaminants. This study aimed to elucidate the connections between diet and the serum metabolic profiles of 1-year-old Finnish children. This master´s thesis used data from Finnish infants (n=439) collected by 3-day food record and questionnaires, in conjunction with metabolite assessments from blood samples collected at the age of 12 months. The investigation particularly focused on cow´s milk products and breast milk. Spearman correlation coefficient served as the primary statistical tool utilising data derived from the DIPP Nutrition study. Infant diets´ primarily comprised various cow´s milk products, milks and infant formulas. Noteworthy findings revealed that distinct lipids and free fatty acids, significantly associated with cow´s milk product consumption and breastfeeding. In the future, this study holds potential for enhancing comprehension of diet-related disease development by employing metabolites as markers to dissect dietary impacts.