Browsing by Subject "Tissue engineering"

This study is a review of literature on stem cell therapies such as bone tissue engineering and their safety. The main focus is on bone tissue engineering done in the neurocranium and viscerocranium with mesenchymal stem cells. Mesenchymal stem cells are considered safe and have been used in numerous clinical case studies. Still many questions are unanswered on their tumorigenic and immunogenic potential. The aim of this study was to analyze the safety of bone tissue engineering with mesenchymal stem cells and to review literature on the most used scaffolds. This study proves that more resources must be used to study the stem cell therapies and their potential risks, find out the optimal biomaterial to be used as a scaffold and to provide a more systematical analysis of all current tissue engineering data on bones. Furthermore, results should be published even of failed studies.